Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793453 | 0.88 | SMN1; SMN2 (0.39) | PTPN1TUBB1GPR84ALDH1A1SMN1; SMN2 | |
| SCHEMBL16997341 | 0.81 | AR (0.41) | PTPN1GPR84CASP1 | |
| SCHEMBL11435326 | 0.81 | ALDH1A1 (0.38) | PTPN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29196089 | 0.79 | PTPN1 (0.32) | PTPN1 | |
| SCHEMBL26605008 | 0.79 | PTPN1 (0.39) | PTPN1ALDH1A1CASP1 | |
| SCHEMBL8840934 | 0.78 | CA1 (0.50) | PTPN1ALDH1A1GLO1 | |
| SCHEMBL19360287 | 0.78 | PTGS2 (0.36) | PTPN1GPR84 | |
| SCHEMBL14216960 | 0.76 | CA1 (0.48) | PTPN1ALDH1A1GLO1 | |
| SCHEMBL12793109 | 0.74 | PTPN1 (0.42) | PTPN1TUBB1ALDH1A1 | |
| SCHEMBL17149439 | 0.74 | TEAD4 (0.54) | TUBB1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7585928-B2 | monomers of acetylenic homo- or copolymers; cured polymers has low dielectric constant as insulating layers in microelectronic devices | DOW GLOBAL TECHNOLOGIES (US) | 2009-09-08 | — | — | US | disclosed |
| US-20070027278-A1 | Multifunctional monomers containing bound mesogenic poragen forming moieties and polyarylene compositions therefrom | DOW GLOBAL TECHNOLOGIES LLC | 2007-02-01 | — | — | US | disclosed |
| WO-2005042613-A1 | MULTIFUNCTIONAL MONOMERS CONTAINING BOUND MESOGENIC PORAGEN FORMING MOIETIES AND POLYARYLENE COMPOSITIONS THEREFROM | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027278-A1 | Multifunctional monomers containing bound mesogenic poragen forming moieties and polyarylene compositions therefrom | LRBA, CD74, BMP2 | PTPN1 3789/4885TUBB1 2905/4885GPR84 1979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.