Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 5/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CTSV | O60911 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4080919 | 0.87 | ALOX5 (0.54) | ALOX5NPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL5716984 | 0.74 | ALOX5 (0.41) | ALOX5MTNR1AMTNR1BCTSVCTSL | |
| SCHEMBL9540894 | 0.71 | HCAR2 (0.34) | — | |
| SCHEMBL3878774 | 0.71 | ALOX5 (0.53) | ALOX5L3MBTL1 | |
| SCHEMBL1344869 | 0.67 | GSK3B (0.46) | GSK3B | |
| SCHEMBL6014774 | 0.61 | KDM4E (0.61) | MTNR1AMTNR1BRAB9AKMT2A | |
| SCHEMBL13469363 | 0.60 | CA1 (0.45) | KMT2A | |
| SCHEMBL7733392 | 0.59 | HTR2A (0.48) | L3MBTL1 | |
| SCHEMBL10928233 | 0.58 | KDM4E (0.36) | KMT2A | |
| SCHEMBL22149262 | 0.57 | GAA (0.56) | DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013182-A2 | AMINOQUINOLONES AS GSK-3 INHIBITORS | Activx Biosciences, Inc. (US) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007106537-A2 | AMINOQUINOLONES AS GSK-3 INHIBITORS | ACTIVX BIOSCIENCES, INC. (US) | 2007-09-20 | — | — | WO | disclosed |