Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6341275 | 0.78 | HCAR2 (0.35) | HCAR2TOP2ATOP2B | |
| SCHEMBL3872372 | 0.71 | ALOX5 (0.38) | — | |
| SCHEMBL6904417 | 0.71 | IDO1 (0.38) | HCAR2KCNH2 | |
| SCHEMBL6004835 | 0.70 | POLB (0.34) | HCAR2POLB | |
| SCHEMBL8341388 | 0.68 | CACNA1F (0.53) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL3870848 | 0.66 | NPSR1 (0.41) | — | |
| SCHEMBL7557799 | 0.65 | ALDH1A1 (0.51) | TOP2ATOP2B | |
| SCHEMBL27566129 | 0.64 | NOTUM (0.37) | HCAR2POLB | |
| SCHEMBL4237180 | 0.63 | PADI4 (0.36) | HCAR2MAPK1 | |
| SCHEMBL13469363 | 0.63 | CA1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559774-A1 | INDIVIDUAL STEREOISOMERS OF 7- 3-(1-AMINOALKYL)-1-PYRROLIDINYL]-QUINOLONES AND NAPHTHYRIDONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-09-15 | — | — | EP | disclosed |