SCHEMBL3873089

SCHEMBL3873089

CCC1(CC)c2c[c]ccc2-c2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PGR P06401 3/20 0.37
APEX1 P27695 1/20 0.36
THRB P10828 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CYP1A2 P05177 2/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32
KCNQ2 O43526 2/20 0.31
CYP2D6 P10635 1/20 0.31
PDK2 Q15119 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30
ELANE P08246 1/20 0.30
ITGA4 P13612 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2407953 0.91
SCHEMBL26130340 0.89 PGR (0.37) PGRAPEX1CYP1A2CYP2C19KMT2A
SCHEMBL2406646 0.87
SCHEMBL1286295 0.86 APEX1 (0.41) PGRAPEX1THRBTDP1PDK2
SCHEMBL2332113 0.83 APEX1 (0.39) PGRAPEX1CYP1A2CYP2C19KMT2A
SCHEMBL29484836 0.82 APEX1 (0.47) PGRAPEX1THRBTDP1CYP1A2
SCHEMBL1394829 0.82 APEX1 (0.47) PGRAPEX1THRBTDP1CYP1A2
SCHEMBL1334440 0.81 MMP2 (0.38) PGRAPEX1TDP1CYP2C19KMT2A
SCHEMBL1335312 0.81 MMP2 (0.38) PGRAPEX1TDP1CYP2C19KMT2A
SCHEMBL2409026 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116997575-A Polymer and application thereof 日产化学株式会社 2023-11-03 CN disclosed
WO-2023189399-A1 POLYMER AND USE THEREOF 日産化学株式会社 2023-10-05 WO disclosed
US-9865823-B2 Quinolinium dyes with fluorinated counter anion for dye sensitized solar cells BASF SE (DE) 2018-01-09 US disclosed
CN-104370801-B Carbazole compound and application thereof 东曹株式会社 2017-11-03 CN disclosed
US-9650565-B2 Carbazole compound and use thereof TOSOH CORPORATION (JP) 2017-05-16 US disclosed
CN-104326968-B Carbazole compound and use thereof 东曹株式会社 2017-04-12 CN disclosed
EP-2772483-B1 4-AMINOCARBAZOLE COMPOUND AND USE OF SAME TOSOH CORP (JP) 2017-03-29 EP disclosed
EP-2006278-B2 BENZOFLUORENE COMPOUND AND USE THEREOF TOSOH CORP (JP) 2016-10-12 EP disclosed
CN-104011022-B 4-aminocarbazole compound and application thereof 东曹株式会社 2016-08-24 CN disclosed
US-20160155575-A1 METHINE DYES WITH LARGE ORGANIC COUNTER ANION FOR DYE SENSITIZED SOLAR CELLS BASF SE (DE) 2016-06-02 US disclosed
CN-101421226-A Benzofluorene compound and use thereof TOSOH CORP (JP) 2009-04-29 CN disclosed
US-7482490-B2 Amine compound having fluorene group as framework, process for producing the amine compound, and use of the amine compound TOSOH CORPORATION (JP) 2009-01-27 US disclosed
EP-2006278-A2 BENZOFLUORENE COMPOUND AND USE THEREOF Tosoh Corporation (JP) 2008-12-24 EP disclosed
US-20080194878-A1 Amine Compound Having Fluorene Group as Framework, Process for Producing the Amine Compound, and Use of the Amine Compound TOSOH CORPORATION (JP) 2008-08-14 US disclosed
US-7189877-B2 Arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices TOSCH CORPORATION (JP) 2007-03-13 US disclosed
EP-1752440-A1 AMINE COMPOUND HAVING FLUORENE GROUP AS FRAMEWORK, PROCESS FOR PRODUCING THE AMINE COMPOUND, AND USE OF THE AMINE COMPOUND Tosoh Corporation (JP) 2007-02-14 EP disclosed
EP-1400578-B1 Electrolumisescent 9,9-bis(4-amino)-1,1'-biphenyl)fluorene derivatives TOSOH CORP (JP) 2005-11-30 EP disclosed
US-20040110958-A1 Novel arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices TOSOH CORPORATION 2004-06-10 US disclosed
EP-1400578-A1 Electrolumisescent 9,9-bis(4-amino)-1,1'-biphenyl)fluorene derivatives Tosoh Corporation (JP) 2004-03-24 EP disclosed
CN-1374315-A Metal complex, illuminated device and display equipment KANON K K (JP) 2002-10-16 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040110958-A1 Novel arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices AHR, NAT1, AR PGR 775/4885APEX1 753/4885THRB 741/4885
US-20080194878-A1 Amine Compound Having Fluorene Group as Framework, Process for Producing the Amine Compound, and Use of the Amine Compound TAAR1, SLC18A1, ADRB2 PGR 1021/4885APEX1 1887/4885THRB 765/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.