Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3871972 | 0.87 | — | — | |
| SCHEMBL3871946 | 0.80 | — | — | |
| SCHEMBL3873107 | 0.77 | HCRTR1 (0.34) | HCRTR1HCRTR2 | |
| SCHEMBL8292289 | 0.74 | CA1 (0.36) | — | |
| SCHEMBL3871976 | 0.74 | HCRTR1 (0.33) | HCRTR1HCRTR2 | |
| SCHEMBL3871136 | 0.71 | — | — | |
| SCHEMBL8362651 | 0.68 | POLB (0.34) | HCRTR1HCRTR2 | |
| SCHEMBL3870481 | 0.68 | POLB (0.34) | HCRTR1HCRTR2 | |
| SCHEMBL3870480 | 0.68 | POLB (0.34) | HCRTR1HCRTR2 | |
| SCHEMBL3870025 | 0.67 | PDK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482448-B2 | Compounds and compositions as cathepsin inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2009-01-27 | — | — | US | disclosed |
| US-20060189657-A1 | Novel compounds and compositions as cathepsin inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189657-A1 | Novel compounds and compositions as cathepsin inhibitors | CTSB, CTSS, CTSK | HCRTR1 3384/4885HCRTR2 3732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.