Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 6/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | RBP4 | P02753 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3660571 | 0.81 | DRD2 (0.62) | DRD4SIGMAR1 | |
| SCHEMBL7202138 | 0.80 | SLC18A3 (0.62) | DRD4SIGMAR1 | |
| SCHEMBL5727474 | 0.79 | DRD2 (0.48) | TERT | |
| SCHEMBL28942169 | 0.79 | RBP4 (0.50) | RBP4 | |
| SCHEMBL23816922 | 0.79 | SLC18A3 (0.60) | DRD4SIGMAR1 | |
| SCHEMBL23772810 | 0.77 | PBRM1 (0.49) | — | |
| SCHEMBL12209849 | 0.76 | ALDH1A1 (0.60) | SIGMAR1 | |
| SCHEMBL3143872 | 0.75 | MEN1 (0.66) | RBP4SIGMAR1 | |
| SCHEMBL7403433 | 0.75 | MAOB (0.49) | MAOAMAOB | |
| SCHEMBL1135373 | 0.75 | TERT (0.41) | TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2086551-A2 | THROMBOPOIETIN MIMETICS | Stategics, Inc. (US) | 2009-08-12 | — | — | EP | claimed |
| US-20080139621-A1 | Thrombopoietin Mimetics | STATEGICS, INC. (US) | 2008-06-12 | — | — | US | claimed |
| WO-2008070583-A2 | THROMBOPOIETIN MIMETICS | STATEGICS, INC. (US) | 2008-06-12 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139621-A1 | Thrombopoietin Mimetics | MPL, THPO, TEK | TERT 367/4885MAOA 4032/4885MAOB 4216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.