Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3871842 | 0.89 | SSTR5 (0.46) | KDM4EALDH1A1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL3883342 | 0.88 | ALDH1A1 (0.43) | KDM4EALDH1A1NPSR1MAPTSMN1; SMN2 | |
| SCHEMBL3873697 | 0.88 | SSTR5 (0.45) | KDM4EALDH1A1SMN1; SMN2MAOB | |
| SCHEMBL3872367 | 0.85 | SSTR5 (0.43) | KDM4EMAOB | |
| SCHEMBL3876134 | 0.84 | SSTR5 (0.49) | KDM4EMAOBATM | |
| SCHEMBL3871203 | 0.83 | DHFR (0.39) | KDM4EALDH1A1SMN1; SMN2LMNAMAOB | |
| SCHEMBL3872725 | 0.83 | KDM4E (0.39) | KDM4EALDH1A1LMNAMAOB | |
| SCHEMBL3873985 | 0.81 | SSTR5 (0.50) | — | |
| SCHEMBL6504152 | 0.78 | CCR8 (0.52) | MAOBKMT2AMEN1 | |
| SCHEMBL6338074 | 0.78 | NPSR1 (0.39) | KDM4ENPSR1LMNAMAOBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893603-B1 | PIPERIDIN-4-YL-AMIDE DERIVATIVES AND THEIR USE AS SST RECEPTOR SUBTYPE 5 ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2009-10-14 | — | — | EP | disclosed |