Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 8/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3873296 | 0.88 | KDM4E (0.53) | KDM4EMAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL3871842 | 0.88 | SSTR5 (0.46) | SSTR5KDM4ESPHK1MAOBMAOA | |
| SCHEMBL3883342 | 0.87 | ALDH1A1 (0.43) | SSTR5HRH1KDM4ESPHK1MAOB | |
| SCHEMBL3872367 | 0.84 | SSTR5 (0.43) | SSTR5KCNH2KDM4ESPHK1MAOB | |
| SCHEMBL3876134 | 0.83 | SSTR5 (0.49) | SSTR5KCNH2KDM4EMAOBMAOA | |
| SCHEMBL3872725 | 0.82 | KDM4E (0.39) | SSTR5KCNH2KDM4ESPHK1MAOB | |
| SCHEMBL3871203 | 0.80 | DHFR (0.39) | SSTR5HRH1KDM4ESPHK1MAOB | |
| SCHEMBL3873985 | 0.80 | SSTR5 (0.50) | SSTR5KCNH2 | |
| SCHEMBL14142405 | 0.79 | GAA (0.46) | KDM4ESPHK1MAOBMAOAALDH1A1 | |
| SCHEMBL6505049 | 0.76 | FAAH (0.48) | KCNH2SPHK1MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893603-B1 | PIPERIDIN-4-YL-AMIDE DERIVATIVES AND THEIR USE AS SST RECEPTOR SUBTYPE 5 ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2009-10-14 | — | — | EP | disclosed |