SCHEMBL3873985

SCHEMBL3873985

CCOc1cc(CN2CC[CH]CC2C(N)=O)cc(OCC)c1-c1ccc(F)cc1

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SSTR5 P35346 20/20 0.50
KCNH2 Q12809 5/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3876134 0.89 SSTR5 (0.49) SSTR5KCNH2
SCHEMBL3872367 0.88 SSTR5 (0.43) SSTR5KCNH2
SCHEMBL3883342 0.84 ALDH1A1 (0.43) SSTR5
SCHEMBL3871842 0.81 SSTR5 (0.46) SSTR5
SCHEMBL3872725 0.81 KDM4E (0.39) SSTR5KCNH2
SCHEMBL3873296 0.81 KDM4E (0.53)
SCHEMBL3873697 0.80 SSTR5 (0.45) SSTR5KCNH2
SCHEMBL2852932 0.79 MAOB (0.47)
SCHEMBL3871203 0.79 DHFR (0.39) SSTR5
SCHEMBL29940195 0.71 SSTR5 (0.66) SSTR5KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1893603-B1 PIPERIDIN-4-YL-AMIDE DERIVATIVES AND THEIR USE AS SST RECEPTOR SUBTYPE 5 ANTAGONISTS HOFFMANN LA ROCHE (CH) 2009-10-14 EP disclosed