Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 7/20 | 0.51 |
| ▸ | F2 | P00734 | 2/20 | 0.51 |
| ▸ | PLG | P00747 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | C1S | P09871 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3151068 | 0.81 | TMPRSS2 (0.43) | PRSS1F2PLGTMPRSS2DRD3 | |
| SCHEMBL8079534 | 0.80 | L3MBTL1 (0.49) | PRSS1F2PLGPRSS2C1S | |
| Hydrochloric Acid SCHEMBL8187022 | 0.78 | MTNR1A (0.51) | PRSS1F2PLGPRSS2C1S | |
| SCHEMBL8934273 | 0.73 | NPC1 (0.50) | — | |
| SCHEMBL10310294 | 0.71 | MTNR1A (0.59) | PRSS1F2PLGPRSS2C1S | |
| SCHEMBL7418889 | 0.71 | TMPRSS2 (0.47) | PRSS1F2PLGPRSS2C1S | |
| SCHEMBL8596426 | 0.71 | MTNR1A (0.59) | DRD3 | |
| SCHEMBL5331717 | 0.71 | LMNA (0.58) | PRSS1F2PLGPRSS2C1S | |
| SCHEMBL16799118 | 0.71 | MAPT (0.35) | ALDH1A1 | |
| SCHEMBL1025 | 0.71 | KCNA3 (0.88) | KCNA3DRD2DRD4DRD3TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7575866-B2 | Intracellular fusion protein comprising a target protein and a detector protein is bound to a membrane-permeable, fluorescently-labeled ligand of the detector protein, thereby providing an adjunct or alternative to Green Fluorescent Protein | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2009-08-18 | — | — | US | disclosed |
| EP-1601576-A4 | LIGAND/BINDING PARTNER BIO-LABELING SYSTEMS | UNIV COLUMBIA (US) | 2007-12-05 | — | — | EP | disclosed |
| US-20060211007-A1 | Ligand/binding partner bio-labeling systems | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2006-09-21 | — | — | US | disclosed |
| EP-1601576-A2 | LIGAND/BINDING PARTNER BIO-LABELING SYSTEMS | The Trustees of Columbia University in the City of New York (US) | 2005-12-07 | — | — | EP | disclosed |
| WO-2004078594-A2 | LIGAND/BINDING PARTNER BIO-LABELING SYSTEMS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2004-09-16 | — | — | WO | disclosed |