Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | CCND1 | P24385 | 1/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12614276 | 0.77 | GPR84 (0.52) | IMPDH2ALDH1A1NR4A2CCNE2CDK4 | |
| SCHEMBL3971661 | 0.75 | ALDH1A1 (0.56) | IMPDH2ALDH1A1NR4A2CCNE2CDK4 | |
| SCHEMBL3867842 | 0.75 | ALDH1A1 (0.47) | IMPDH2ALDH1A1NR4A2CCNE2CDK4 | |
| SCHEMBL1606642 | 0.74 | GPR84 (0.48) | IMPDH2ALDH1A1NR4A2CCNE2CDK4 | |
| SCHEMBL10698031 | 0.74 | NR4A2 (0.53) | IMPDH2ALDH1A1NR4A2GPR84POLB | |
| SCHEMBL3416860 | 0.74 | NR4A2 (0.53) | IMPDH2ALDH1A1NR4A2GPR84POLB | |
| SCHEMBL8500052 | 0.72 | NR4A2 (0.51) | IMPDH2ALDH1A1NR4A2GPR84CCNT1 | |
| SCHEMBL30058738 | 0.71 | NR4A2 (0.50) | IMPDH2ALDH1A1NR4A2CCNE2CDK4 | |
| SCHEMBL27383813 | 0.71 | NR4A2 (0.46) | IMPDH2ALDH1A1NR4A2CCNE2CDK4 | |
| SCHEMBL2350154 | 0.71 | NR4A2 (0.50) | IMPDH2ALDH1A1NR4A2GPR84CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009102384-A2 | RADIOLABELED DERIVATIVES OF POTENT CHYMASE INHIBITORS | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2009-08-20 | — | — | WO | disclosed |
| US-20090169475-A1 | RADIOLABELED DERIVATIVES OF POTENT CHYMASE INHIBITORS | MOLECULAR INSIGHT PHARMACEUTICALS, INC. | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090169475-A1 | RADIOLABELED DERIVATIVES OF POTENT CHYMASE INHIBITORS | CMA1, CPA3, CPA1 | IMPDH2 2956/4885ALDH1A1 1425/4885NR4A2 4083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.