SCHEMBL3874497

SCHEMBL3874497

Cc1ccc(-c2ccccc2OP(O)O)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SYK P43405 1/20 0.46
LMNA P02545 4/20 0.45
L3MBTL1 Q9Y468 3/20 0.45
MAPK1 P28482 2/20 0.45
TDP1 Q9NUW8 1/20 0.45
ALDH1A1 P00352 3/20 0.40
ADRA2A P08913 1/20 0.40
ADRA2B P18089 1/20 0.40
ADRA2C P18825 1/20 0.40
HTT P42858 1/20 0.40
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
POLB P06746 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.37
RAB9A P51151 2/20 0.37
GLA P06280 1/20 0.37
PAX8 Q06710 1/20 0.37
MAPT P10636 3/20 0.36
GAA P10253 2/20 0.36
NPC1 O15118 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8040839 0.98 SYK (0.45) SYKLMNAL3MBTL1MAPK1TDP1
SCHEMBL8040741 0.86 SYK (0.50) SYKLMNAL3MBTL1MAPK1TDP1
SCHEMBL8040823 0.85 SYK (0.49) SYKLMNAL3MBTL1MAPK1TDP1
SCHEMBL4965147 0.84 SYK (0.37) SYKLMNAL3MBTL1MAPK1TDP1
SCHEMBL8160159 0.84 TDP1 (0.44) LMNAL3MBTL1MAPK1TDP1ALDH1A1
SCHEMBL29992101 0.84 TDP1 (0.44) LMNAL3MBTL1MAPK1TDP1ALDH1A1
SCHEMBL8040829 0.80 SYK (0.45) SYKLMNAL3MBTL1MAPK1TDP1
SCHEMBL7595690 0.80 CA1 (0.33) LMNAALDH1A1MAPTGAAKDM4E
SCHEMBL11499533 0.78 SYK (0.53) SYKLMNAL3MBTL1MAPK1TDP1
SCHEMBL3880761 0.77 AKR1C3 (0.40) LMNAL3MBTL1MAPK1TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7517838-B2 Lubricating oil for bearing NEW JAPAN CHEMICAL CO., LTD. (JP) 2009-04-14 US disclosed
US-20060019840-A1 Lubricating oil for bearing NEW JAPAN CHEMICAL CO., LTD. (JP) 2006-01-26 US disclosed
EP-0438638-B1 Process for producing norcamphane dicarbonitriles MITSUI CHEMICALS INC (JP) 2000-07-05 EP disclosed
WO-1992004386-A1 SINGLE SOLVENT PROCESS FOR PREPARATION OF GLUTARIMIDE CONTAINING POLYMERS THE DOW CHEMICAL COMPANY (US) 1992-03-19 WO disclosed
US-5094807-A Cyclohexanol, amidation, cycloimidation THE DOW CHEMICAL COMPANY (US) 1992-03-10 US disclosed
US-5087722-A Catalytic hydrocyanation of bicyclo(2.2.1)-5-heptene-2-carbonitrile MITSUI TOATSU CHEMICALS, INC. (JP) 1992-02-11 US disclosed
EP-0155567-B1 LIGHT-TRANSMITTING FIBER MITSUBISHI RAYON CO., LTD. (JP) 1991-12-04 EP disclosed
EP-0438638-A1 Process for producing norcamphane dicarbonitriles MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-07-31 EP disclosed
EP-0234726-B1 METHACRYLATE RESIN COMPOSITION AND PROCESS FOR ITS PREPARATION MITSUBISHI RAYON CO., LTD. (JP) 1991-03-13 EP disclosed
US-4745159-A Methacrylate resin composition and process for its preparation MITSUBISHI RAYON CO., LTD. (JP) 1988-05-17 US disclosed
US-4693553-A Light-transmitting fiber MITSUBISHI RAYON COMPANY LTD. (JP) 1987-09-15 US disclosed
EP-0234726-A2 Methacrylate resin composition and process for its preparation MITSUBISHI RAYON CO., LTD. (JP) 1987-09-02 EP disclosed
EP-0155567-A2 Light-transmitting fiber MITSUBISHI RAYON CO., LTD. (JP) 1985-09-25 EP disclosed