SCHEMBL7595690

SCHEMBL7595690

OP(O)Oc1ccccc1-c1ccccc1OP(O)O

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA12 O43570 1/20 0.33
CA4 P22748 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
APP P05067 1/20 0.32
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.32
HTR7 P34969 1/20 0.31
ALDH1A1 P00352 1/20 0.30
MAPT P10636 2/20 0.30
JAK2 O60674 1/20 0.30
LMNA P02545 1/20 0.30
GAA P10253 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ENPP2 Q13822 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31604211 0.89 ALDH1A1 (0.41) CA1CA2CA12CA4CA7
SCHEMBL29992101 0.86 TDP1 (0.44) TP53HTR7ALDH1A1LMNAKDM4E
SCHEMBL8160159 0.86 TDP1 (0.44) TP53HTR7ALDH1A1LMNAKDM4E
SCHEMBL2571438 0.86 CA2 (0.38) CA1CA2CA12CA4CA7
SCHEMBL3880762 0.82 TRPA1 (0.36) TP53ALDH1A1MAPTLMNAGAA
SCHEMBL339290 0.80 CA1 (0.31) CA1CA2CA12CA4CA7
SCHEMBL7537424 0.80 NR3C1 (0.34) CA1CA2CA12CA4CA7
SCHEMBL3880761 0.80 AKR1C3 (0.40) TP53TSHRALDH1A1MAPTLMNA
SCHEMBL3874497 0.80 SYK (0.46) HTR7ALDH1A1MAPTLMNAGAA
SCHEMBL8040839 0.78 SYK (0.45) ALDH1A1MAPTLMNAGAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4351759-A OXIDATION RESISTANCE, OLEFIN POLYMERS CIBA-GEIGY CORPORATION (US) 1982-09-28 US claimed
US-4288391-A STABILIZERS FOR POLYMERS AND LUBRICANTS CIBA-GEIGY CORPORATION (US) 1981-09-08 US claimed
EP-1249444-A1 Continuous hydroformylation process for forming an aldehyde DSM N.V. (NL) 2002-10-16 EP disclosed
EP-0590611-B1 Process for stabilizing phosphate ligands UNION CARBIDE CHEM PLASTIC (US) 1997-12-17 EP disclosed
EP-0590613-B1 Improved hydroformylation process UNION CARBIDE CHEM PLASTIC (US) 1997-01-08 EP disclosed
EP-0710677-A2 Process for producing stabilized olefin polymers CIBA-GEIGY AG (CH) 1996-05-08 EP disclosed
US-5364950-A Process for stabilizing phosphite ligands in hydroformylation reaction mixtures UNION CARBIDE CHIMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1994-11-15 US disclosed
EP-0590613-A2 Improved hydroformylation process UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1994-04-06 EP disclosed
EP-0590611-A1 Process for stabilizing phosphate ligands UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1994-04-06 EP disclosed
US-5288918-A Using a rhodium-organobisphosphite complex catalyst UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1994-02-22 US disclosed
US-5238979-A Bisphenol phosphites and a phenol ASAHI DENKA KOGYO K.K. (JP) 1993-08-24 US disclosed
US-4605692-A USED IN POLYMERS AND OILS TO PREVENT LIGHT, HEAT, OR AIR DEGRADATION CIBA-GEIGY CORPORATION (US) 1986-08-12 US disclosed
EP-0149259-A2 Alkylidene bisphenol phosphites and phosphates having 2,2,6,6-tetramethyl piperidinyl groups and synthetic resin compositions ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1985-07-24 EP disclosed
US-4524166-A STABILIZERS FOR POLYMERS AND LUBRICATING OILS CIBA-GEIGY CORPORATION (US) 1985-06-18 US disclosed
US-4374219-A STABILIZERS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1983-02-15 US disclosed
US-4351759-A OXIDATION RESISTANCE, OLEFIN POLYMERS CIBA-GEIGY CORPORATION (US) 1982-09-28 US disclosed
US-4318845-A STABILIZERS CIBA-GEIGY CORPORATION (US) 1982-03-09 US disclosed
US-4288391-A STABILIZERS FOR POLYMERS AND LUBRICANTS CIBA-GEIGY CORPORATION (US) 1981-09-08 US disclosed
US-4196117-A Alkylated 1,1'-biphenyl-2,2'-diyl phosphites and stabilized compositions CIBA-GEIGY CORPORATION (US) 1980-04-01 US disclosed
US-4196117-A Alkylated 1,1'-biphenyl-2,2'-diyl phosphites and stabilized compositions CIBA-GEIGY CORPORATION (US) 1980-04-01 US disclosed