Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 5/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8040741 | 0.85 | SYK (0.50) | SYKLMNAMAPK1L3MBTL1TDP1 | |
| SCHEMBL8040823 | 0.83 | SYK (0.49) | SYKLMNAMAPK1L3MBTL1TDP1 | |
| SCHEMBL3874497 | 0.80 | SYK (0.46) | SYKLMNAMAPK1L3MBTL1TDP1 | |
| SCHEMBL8040839 | 0.79 | SYK (0.45) | SYKLMNAMAPK1L3MBTL1TDP1 | |
| SCHEMBL11499533 | 0.77 | SYK (0.53) | SYKLMNAMAPK1L3MBTL1TDP1 | |
| SCHEMBL4425113 | 0.75 | SYK (0.56) | SYKLMNAMAPK1L3MBTL1TDP1 | |
| SCHEMBL9418893 | 0.74 | LMNA (0.47) | SYKLMNAMAPK1L3MBTL1TDP1 | |
| SCHEMBL26509862 | 0.73 | SYK (0.50) | SYKLMNAMAPK1L3MBTL1TDP1 | |
| SCHEMBL27435568 | 0.72 | SYK (0.49) | SYKLMNAMAPK1L3MBTL1TDP1 | |
| SCHEMBL8040845 | 0.71 | CA12 (0.46) | MAPK1RAB9ASMN1; SMN2NPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438638-B1 | Process for producing norcamphane dicarbonitriles | MITSUI CHEMICALS INC (JP) | 2000-07-05 | — | — | EP | disclosed |
| US-5087722-A | Catalytic hydrocyanation of bicyclo(2.2.1)-5-heptene-2-carbonitrile | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0438638-A1 | Process for producing norcamphane dicarbonitriles | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-07-31 | — | — | EP | disclosed |