SCHEMBL4965147

SCHEMBL4965147

Cc1ccc(-c2cccc(OP(O)O)c2-c2ccc(C)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SYK P43405 1/20 0.37
LMNA P02545 2/20 0.36
MAPK1 P28482 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ENPP1 P22413 1/20 0.35
MCL1 Q07820 2/20 0.33
KDR P35968 3/20 0.33
ADORA3 P0DMS8 1/20 0.33
ADRA2A P08913 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HTT P42858 1/20 0.33
BRAF P15056 1/20 0.32
GPR84 Q9NQS5 1/20 0.32
PDCD1 Q15116 1/20 0.32
CD274 Q9NZQ7 1/20 0.32
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL675482 0.84 HNF4A (0.38) LMNAMAPK1TDP1L3MBTL1ALDH1A1
SCHEMBL29924556 0.84 HNF4A (0.38) LMNAMAPK1TDP1L3MBTL1ALDH1A1
SCHEMBL3874497 0.84 SYK (0.46) SYKLMNAMAPK1TDP1L3MBTL1
SCHEMBL9621329 0.84 HDAC4 (0.46) SYKENPP1ADORA3BRAFMEN1
SCHEMBL8040839 0.83 SYK (0.45) SYKLMNAMAPK1TDP1L3MBTL1
SCHEMBL9621386 0.76 SLC6A3 (0.33) TDP1ALDH1A1HTTGPR84MEN1
SCHEMBL449110 0.74 INPPL1 (0.47) SYKLMNAMAPK1TDP1L3MBTL1
SCHEMBL28420810 0.74 HNF4A (0.38) LMNAMAPK1TDP1L3MBTL1ALDH1A1
SCHEMBL11336681 0.74 MYC (0.41) LMNAALDH1A1HTTMEN1KMT2A
SCHEMBL8468313 0.73 PDK2 (0.35) LMNAMAPK1TDP1ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080319138-A1 Initiator Systems for Use in Curing Unsaturated Resins, and Curable Compositions and Methods For Curing Them ALBEMARLE CORPORATION (US) 2008-12-25 US disclosed
EP-1957573-A1 INITIATOR SYSTEMS FOR USE IN CURING UNSATURATED RESINS, AND CURABLE COMPOSITIONS AND METHODS FOR CURING THEM Albermarle Corporation (US) 2008-08-20 EP disclosed
WO-2007067859-A1 INITIATOR SYSTEMS FOR USE IN CURING UNSATURATED RESINS, AND CURABLE COMPOSITIONS AND METHODS FOR CURING THEM ALBEMARLE CORPORATION (US) 2007-06-14 WO disclosed