Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP1A1 | P05023 | 3/20 | 0.74 |
| ▸ | ATP1B1 | P05026 | 3/20 | 0.74 |
| ▸ | ATP1A3 | P13637 | 3/20 | 0.74 |
| ▸ | ATP1B2 | P14415 | 3/20 | 0.74 |
| ▸ | ATP1A2 | P50993 | 3/20 | 0.74 |
| ▸ | ATP1B3 | P54709 | 3/20 | 0.74 |
| ▸ | FXYD2 | P54710 | 3/20 | 0.74 |
| ▸ | ATP1A4 | Q13733 | 3/20 | 0.74 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.74 |
| ▸ | PKLR | P30613 | 1/20 | 0.61 |
| ▸ | GALNT2 | Q10471 | 1/20 | 0.61 |
| ▸ | GALNT1 | Q10472 | 1/20 | 0.61 |
| ▸ | GALNT3 | Q14435 | 1/20 | 0.61 |
| ▸ | GALNT10 | Q86SR1 | 1/20 | 0.61 |
| ▸ | GALNT13 | Q8IUC8 | 1/20 | 0.61 |
| ▸ | GALNT6 | Q8NCL4 | 1/20 | 0.61 |
| ▸ | GALNT14 | Q96FL9 | 1/20 | 0.61 |
| ▸ | MET | P08581 | 1/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1444851 | 0.85 | ATP1A1 (1.00) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL30451609 | 0.85 | ATP1A1 (1.00) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL3881176 | 0.80 | PTGS2 (0.74) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL7984298 | 0.79 | ESR2 (0.75) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL7987277 | 0.77 | ESR2 (0.70) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL7980209 | 0.77 | PKLR (1.00) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL29370098 | 0.77 | PKLR (1.00) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL7227954 | 0.76 | ATP1A1 (0.79) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL151934 | 0.76 | ATP1A1 (1.00) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL7238197 | 0.76 | ATP1A1 (0.72) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080098535-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof | GLENN ROBERT W JR | 2008-05-01 | — | — | US | claimed |
| US-20050217038-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-10-06 | — | — | US | claimed |
| US-7491245-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2009-02-17 | — | — | US | disclosed |
| US-20080098535-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof | GLENN ROBERT W JR | 2008-05-01 | — | — | US | disclosed |
| US-7331997-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-02-19 | — | — | US | disclosed |
| EP-1735059-A2 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | The Procter and Gamble Company (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005099656-A2 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2005-10-27 | — | — | WO | disclosed |
| US-20050217038-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050217038-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, CKMT1A; CKMT1B, TUBB6 | ATP1A1 2526/4885ATP1B1 1496/4885ATP1A3 2486/4885 |
| US-20080098535-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof | KRT18, CKMT1A; CKMT1B, TUBB6 | ATP1A1 2526/4885ATP1B1 1496/4885ATP1A3 2486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.