Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 3/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.43 |
| ▸ | PTPN4 | P29074 | 1/20 | 0.43 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.36 |
| ▸ | DUSP6 | Q16828 | 1/20 | 0.36 |
| ▸ | LPL | P06858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3877397 | 0.87 | PTPRB (0.40) | PTPRBPTPN2PTPN1PTPN11PTPN4 | |
| SCHEMBL1173905 | 0.73 | HTT (0.52) | CNR1CNR2PTGS2CYP3A4HTT | |
| SCHEMBL1473025 | 0.72 | PTPRB (0.37) | PTPRBPTPN2PTPN1PTPN11PTPN4 | |
| SCHEMBL542181 | 0.71 | PTGS2 (0.55) | CNR1CNR2PTGS2CYP3A4HTT | |
| SCHEMBL12514479 | 0.71 | TTR (0.48) | CNR1CNR2PTGS2CYP3A4HTT | |
| SCHEMBL1023215 | 0.71 | DHFR (0.45) | PTPN1PTPN11CNR1CNR2PTGS2 | |
| SCHEMBL18538254 | 0.71 | PTPN2 (0.50) | PTPRBPTPN2PTPN1PTPN11PTPN4 | |
| SCHEMBL4900256 | 0.71 | CNR1 (0.50) | CNR1CNR2NPC1MAPK1RAB9A | |
| Ammonia Solution, Strong SCHEMBL2441862 | 0.71 | CNR1 (0.45) | CNR1CNR2LPLLIPGALOX5 | |
| SCHEMBL7700304 | 0.71 | CNR1 (0.46) | CNR1CNR2PTGS2CYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7585928-B2 | monomers of acetylenic homo- or copolymers; cured polymers has low dielectric constant as insulating layers in microelectronic devices | DOW GLOBAL TECHNOLOGIES (US) | 2009-09-08 | — | — | US | disclosed |
| US-20070027278-A1 | Multifunctional monomers containing bound mesogenic poragen forming moieties and polyarylene compositions therefrom | DOW GLOBAL TECHNOLOGIES LLC | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027278-A1 | Multifunctional monomers containing bound mesogenic poragen forming moieties and polyarylene compositions therefrom | LRBA, CD74, BMP2 | PTPRB 600/4885PTPN2 3245/4885PTPN1 3789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.