Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 2/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.34 |
| ▸ | PTPN4 | P29074 | 1/20 | 0.34 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14174487 | 0.77 | GAA (0.47) | PTGS2CYP3A4HPGDMAPK1HTT | |
| SCHEMBL17442492 | 0.74 | ALDH1A1 (0.36) | PTGS2CYP3A4HPGD | |
| SCHEMBL15736943 | 0.73 | IDO1 (0.34) | — | |
| SCHEMBL16669329 | 0.73 | ESR1 (0.52) | PTGS2CYP3A4 | |
| SCHEMBL15736593 | 0.72 | NOS3 (0.31) | — | |
| SCHEMBL14226990 | 0.72 | PTGS2 (0.46) | PTGS2 | |
| SCHEMBL16669388 | 0.72 | CALM1 (0.47) | — | |
| SCHEMBL3875014 | 0.72 | PTPRB (0.48) | PTPRBPTPN2PTPN1PTPN11PTPN4 | |
| SCHEMBL3917416 | 0.71 | HRH1 (0.44) | CYP3A4NPC1HTT | |
| SCHEMBL15736353 | 0.70 | IDO1 (0.40) | CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915438-B1 | Solid phase host compositions | NORTHWESTERN UNIVERSITY (US) | 2011-03-29 | — | — | US | disclosed |
| US-7271259-B1 | Solid phase host compositions | NORTHWESTERN UNIVERSITY (US) | 2007-09-18 | — | — | US | disclosed |