Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 4/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5147469 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2TSHRARESR1ESR2 | |
| SCHEMBL6678297 | 0.82 | SMN1; SMN2 (0.37) | SMN1; SMN2POLBTSHRGAAGLA | |
| SCHEMBL7761954 | 0.78 | ALDH1A1 (0.55) | POLBTSHRGAAESR2CASP1 | |
| SCHEMBL28201831 | 0.77 | PGR (0.51) | SMN1; SMN2POLBTSHRGAAGLA | |
| SCHEMBL27224485 | 0.76 | ALDH1A1 (0.37) | SMN1; SMN2POLBTSHRGAAGLA | |
| SCHEMBL2443511 | 0.75 | ALDH1A1 (0.38) | SMN1; SMN2TSHRGAACASP1MAPT | |
| SCHEMBL17312034 | 0.73 | SMN1; SMN2 (0.39) | SMN1; SMN2POLBTSHRGAAGLA | |
| SCHEMBL9357030 | 0.72 | LMNA (0.49) | SMN1; SMN2TSHRGAAMAPTMEN1 | |
| SCHEMBL9503147 | 0.72 | TSHR (0.43) | SMN1; SMN2POLBTSHRGAAGLA | |
| SCHEMBL10002095 | 0.71 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBTSHRGAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601180-B2 | Use for the dyeing with lightening effect of keratin substances of a composition comprising a fluorescent cyanine dye | L'OREAL S.A. (FR) | 2009-10-13 | — | — | US | disclosed |