SCHEMBL3876878

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3873190	0.83	KCNA3 (0.45)	BRAFHTTLMNARAB9AHPGD
	SCHEMBL3875328	0.74	NPC1 (0.39)	EGFRHTTALDH1A1MAPTNPC1
	SCHEMBL15485307	0.72	IDO1 (0.44)	BRAFHTTALDH1A1MAPTNPC1
	SCHEMBL3875440	0.72	KDR (0.42)	EGFRBRAFALDH1A1MAPTMAPK1
	SCHEMBL5778714	0.72	TRPA1 (0.48)	EGFRALDH1A1MAPTNPC1LMNA
	SCHEMBL15490439	0.72	SMN1; SMN2 (0.41)	BRAFHTTALDH1A1MAPTNPC1
	SCHEMBL1285186	0.72	CYP1A2 (0.44)	BRAFHTTMAPTLMNASMN1; SMN2
	SCHEMBL307909	0.72	MEN1 (0.49)	EGFRHTTALDH1A1MAPTNPC1
	SCHEMBL22567997	0.71	GAA (0.43)	HTTALDH1A1MAPTNPC1LMNA
	SCHEMBL7790214	0.71	HAO1 (0.47)	HTTMAPTNPC1LMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.