Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | PPIA | P62937 | 4/20 | 0.35 |
| ▸ | CTSV | O60911 | 3/20 | 0.35 |
| ▸ | CTSL | P07711 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | PPIF | P30405 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | MAX | P61244 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3877870 | 1.00 | SMN1; SMN2 (0.40) | SMN1; SMN2PKMHPGDPTGESMAPT | |
| SCHEMBL3586711 | 0.92 | PTGES (0.42) | PTGESMAPTNPC1RAB9APPIA | |
| SCHEMBL3586707 | 0.92 | PTGES (0.42) | PTGESMAPTNPC1RAB9APPIA | |
| SCHEMBL3586703 | 0.92 | PTGES (0.42) | PTGESMAPTNPC1RAB9APPIA | |
| SCHEMBL1447461 | 0.85 | PTGES (0.40) | SMN1; SMN2PKMHPGDPTGESMAPT | |
| SCHEMBL3587958 | 0.83 | PPIA (0.41) | PTGESMAPTNPC1RAB9APPIA | |
| SCHEMBL4942728 | 0.81 | SMN1; SMN2 (0.37) | SMN1; SMN2PKMHPGDPTGESMAPT | |
| SCHEMBL30105376 | 0.74 | RAB9A (0.46) | SMN1; SMN2PKMPTGESMAPTNPC1 | |
| SCHEMBL3593506 | 0.74 | CTSV (0.42) | PTGESMAPTNPC1RAB9APPIA | |
| SCHEMBL3593504 | 0.73 | NPC1 (0.45) | SMN1; SMN2PKMPTGESMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2027091-A1 | NEW PHARMACEUTICAL COMPOUNDS | BIAL - Portela & Ca., S.A. (PT) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007117165-A1 | NEW PHARMACEUTICAL COMPOUNDS | BIAL - PORTELA & CA, S.A. (PT) | 2007-10-18 | — | — | WO | disclosed |