Folic Acid

Folic Acid

SCHEMBL3878

Nc1nc(O)c2nc(CNc3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc3)cnc2n1

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.73
MEN1 O00255 2/20 0.73
ALDH1A1 P00352 2/20 0.73
TYMS P04818 2/20 0.73
POLB P06746 2/20 0.73
HPGD P15428 2/20 0.73
KMT2A Q03164 2/20 0.73
HSD17B10 Q99714 2/20 0.73
TDP1 Q9NUW8 2/20 0.73
GAA P10253 1/20 0.73
AKR1B1 P15121 1/20 0.73
TSHR P16473 1/20 0.73
PTGS2 P35354 1/20 0.73
DHFR P00374 9/20 0.67
TLR4 O00206 1/20 0.61
LMNA P02545 1/20 0.61
TP53 P04637 1/20 0.61
GLA P06280 1/20 0.61
HMGB1 P09429 1/20 0.61
MAPT P10636 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Folic Acid SCHEMBL6470174 1.00 KDM4E (0.73) KDM4EMEN1ALDH1A1TYMSPOLB
Folic Acid SCHEMBL29677832 1.00 KDM4E (0.73) KDM4EMEN1ALDH1A1TYMSPOLB
Folic Acid SCHEMBL12148554 1.00 KDM4E (0.73) KDM4EMEN1ALDH1A1TYMSPOLB
Folic Acid SCHEMBL1887022 0.99 KDM4E (0.72) KDM4EMEN1ALDH1A1TYMSPOLB
Folic Acid SCHEMBL12497751 0.99 KDM4E (0.72) KDM4EMEN1ALDH1A1TYMSPOLB
Folic Acid SCHEMBL23388805 0.99 KDM4E (0.72) KDM4EMEN1ALDH1A1TYMSPOLB
Folic Acid SCHEMBL19837676 0.99 KDM4E (0.72) KDM4EMEN1ALDH1A1TYMSPOLB
Folic Acid SCHEMBL652283 0.99 KDM4E (0.72) KDM4EMEN1ALDH1A1TYMSPOLB
Folic Acid SCHEMBL22441084 0.99 KDM4E (0.72) KDM4EMEN1ALDH1A1TYMSPOLB
Folic Acid SCHEMBL842691 0.99 KDM4E (0.72) KDM4EMEN1ALDH1A1TYMSPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 266748 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144836-A1 NUTRACEUTICAL FOR ENHANCED COGNITIVE PERFORMANCE Herbanized Wellness, LLC (US) 2026-05-28 US claimed
US-20260144835-A1 MULTIFUNCTIONAL NUTRACEUTICAL FOR ENHANCING FEMALE HEALTH Beltran, Robert R. (US) 2026-05-28 US claimed
EP-4748859-A2 CHEMICALLY AND PHOTOCHEMICALLY INITIATED CELL MEMBRANE BLEBBING TO INDUCE CELL VESICLE PRODUCTION, MODIFICATIONS THEREOF, AND USES THEREOF The Regents of the University of California (US) 2026-05-27 EP claimed
EP-4746716-A1 FAST-ACTING DISINFECTANT COMPOSITION Arxada, LLC (US) 2026-05-27 EP claimed
CN-122075740-A Targeted temperature-sensitive drug-loaded composite microsphere based on attapulgite 2026-05-26 CN claimed
CN-122081234-A Low-serum MSB1 suspension medium and chicken infectious anemia virus inactivated vaccine 2026-05-26 CN claimed
CN-122081310-A Screening method of high-specificity nucleic acid aptamer and specific lactobacillus helveticus aptamer 2026-05-26 CN claimed
US-12635714-B2 Compositions and methods for providing a health benefit to a growing animal Société des Produits Nestlé S.A. (CH) 2026-05-26 US claimed
CN-121379932-B Culture medium for high-density serum-free suspension culture of BHK-21 cells and application thereof Zhongsheng tianxinhe (Wuxi) Biotechnology Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-118318936-B Functional feed for improving quality of cabin-cultured large yellow croaker OCEAN UNIVERSITY OF CHINA (CN) 2026-05-26 CN claimed
US-4058122-A Osmotic system with laminated wall formed of different materials ALZA CORPORATION (US) 1977-11-15 US claimed
US-4053593-A PREVENTING AND CURING DISEASES IN FISH FRUMOFF LEW 1977-10-11 US claimed
US-4049494-A Vaccine production process THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1977-09-20 US claimed
US-4042733-A Forming solid, adhesive-free composite of membrane filters and cellulosic cardboard BOEHRINGER INGELHEIM GMBH (DT) 1977-08-16 US claimed
US-4028465-A BUFFERS, STABILIZED WITH A DITHIO-POLYOL BIO-RAD LABORATORIES (US) 1977-06-07 US claimed
US-4001583-A COVALENTLY BOUND BIOLOGICAL SUBSTANCES TO PLASTIC MATERIALS AND USE IN RADIOASSAY BARRETT M JAMES 1977-01-04 US claimed
US-3989812-A Folic acid derivatives and use in radio-assay SMITHKLINE INSTRUMENTS, INC. (US) 1976-11-02 US claimed
US-3988431-A FOLIC ACID STANDARD BECTON, DICKINSON AND COMPANY (US) 1976-10-26 US claimed
US-3972991-A MEASUREMENT OF FOLATE IN A BLOOD SERUM CASE WESTERN RESERVE UNIVERSITY (US) 1976-08-03 US claimed
US-3960757-A HYDROPHOBIC TOYO JOZO CO., LTD. (JA) 1976-06-01 US claimed