Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | TYMS | P04818 | 2/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.72 |
| ▸ | DHFR | P00374 | 9/20 | 0.66 |
| ▸ | TLR4 | O00206 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Folic Acid SCHEMBL28873655 | 1.00 | KDM4E (0.72) | KDM4EMEN1ALDH1A1TYMSPOLB | |
| Folic Acid SCHEMBL12148554 | 0.99 | KDM4E (0.73) | KDM4EMEN1ALDH1A1TYMSPOLB | |
| Folic Acid SCHEMBL29677832 | 0.99 | KDM4E (0.73) | KDM4EMEN1ALDH1A1TYMSPOLB | |
| Folic Acid SCHEMBL3878 | 0.99 | KDM4E (0.73) | KDM4EMEN1ALDH1A1TYMSPOLB | |
| Folic Acid SCHEMBL6470174 | 0.99 | KDM4E (0.73) | KDM4EMEN1ALDH1A1TYMSPOLB | |
| Folic Acid SCHEMBL23388805 | 0.98 | KDM4E (0.72) | KDM4EMEN1ALDH1A1TYMSPOLB | |
| Folic Acid SCHEMBL12497751 | 0.98 | KDM4E (0.72) | KDM4EMEN1ALDH1A1TYMSPOLB | |
| Folic Acid SCHEMBL652283 | 0.98 | KDM4E (0.72) | KDM4EMEN1ALDH1A1TYMSPOLB | |
| Folic Acid SCHEMBL22441084 | 0.98 | KDM4E (0.72) | KDM4EMEN1ALDH1A1TYMSPOLB | |
| Folic Acid SCHEMBL1887022 | 0.98 | KDM4E (0.72) | KDM4EMEN1ALDH1A1TYMSPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105440035-B | A kind of low energy consumption synthesizes high-purity folic acid preparation method | 北京斯利安药业有限公司 | 2018-02-09 | — | — | CN | claimed |
| CN-105440035-A | Low-energy-consumption preparation method for synthesizing high-purity folic acid | BEIJING SCRIANEN PHARMACEUTICAL CO LTD | 2016-03-30 | — | — | CN | claimed |
| US-20130142888-A1 | N-ACETYL-DL-LEUCINE, NEUROPROTECTIVE AND RETINOPROTECTIVE MEDICAMENT | Rekik, Raouf (TN) | 2013-06-06 | — | — | US | claimed |
| CN-116887702-A | Methods for reducing the incidence or risk of cerebral folate deficiency | 乔治·阿尤布 | 2023-10-13 | — | — | CN | disclosed |
| CN-109788782-A | Folic acid cud bypasses method and composition | 金宝公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-105440035-B | A kind of low energy consumption synthesizes high-purity folic acid preparation method | 北京斯利安药业有限公司 | 2018-02-09 | — | — | CN | disclosed |
| CN-105440035-A | Low-energy-consumption preparation method for synthesizing high-purity folic acid | BEIJING SCRIANEN PHARMACEUTICAL CO LTD | 2016-03-30 | — | — | CN | disclosed |
| US-20160050962-A1 | Preconception/Prenatal/Postnatal Optimal Nutrition System, Compositions and Kits for Use Therein, and Methods of Making and Using Same | NESTEC SA (CH) | 2016-02-25 | — | — | US | disclosed |
| WO-2016027252-A1 | PRECONCEPTION/PRENATAL/POSTNATAL OPTIMAL NUTRITION SYSTEM, COMPOSITIONS AND KITS FOR USE THEREIN, AND METHODS OF MAKING AND USING SAME | NESTEC S.A. (CH) | 2016-02-25 | — | — | WO | disclosed |
| US-20090275505-A1 | Compositions and Methods For Preventing or Treating Feline Chronic Renal Failure | HILL'S PET NUTRITION, INC. (US) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130142888-A1 | N-ACETYL-DL-LEUCINE, NEUROPROTECTIVE AND RETINOPROTECTIVE MEDICAMENT | NLN, ALDH1A2, SIRT1 | KDM4E 3833/4885MEN1 2056/4885ALDH1A1 427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.