Folic Acid

Folic Acid

SCHEMBL652283

Nc1nc(O)c2nc(CNc3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc3)cnc2n1.[NaH]

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.72
MEN1 O00255 2/20 0.72
ALDH1A1 P00352 2/20 0.72
TYMS P04818 2/20 0.72
POLB P06746 2/20 0.72
HPGD P15428 2/20 0.72
KMT2A Q03164 2/20 0.72
HSD17B10 Q99714 2/20 0.72
TDP1 Q9NUW8 2/20 0.72
GAA P10253 1/20 0.72
AKR1B1 P15121 1/20 0.72
TSHR P16473 1/20 0.72
PTGS2 P35354 1/20 0.72
DHFR P00374 9/20 0.66
TLR4 O00206 1/20 0.60
LMNA P02545 1/20 0.60
TP53 P04637 1/20 0.60
GLA P06280 1/20 0.60
HMGB1 P09429 1/20 0.60
MAPT P10636 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Folic Acid SCHEMBL28302576 1.00 KDM4E (0.72) KDM4EMEN1ALDH1A1TYMSPOLB
Folic Acid SCHEMBL6470174 0.99 KDM4E (0.73) KDM4EMEN1ALDH1A1TYMSPOLB
Folic Acid SCHEMBL12148554 0.99 KDM4E (0.73) KDM4EMEN1ALDH1A1TYMSPOLB
Folic Acid SCHEMBL3878 0.99 KDM4E (0.73) KDM4EMEN1ALDH1A1TYMSPOLB
Folic Acid SCHEMBL29677832 0.99 KDM4E (0.73) KDM4EMEN1ALDH1A1TYMSPOLB
Folic Acid SCHEMBL23388805 0.98 KDM4E (0.72) KDM4EMEN1ALDH1A1TYMSPOLB
Folic Acid SCHEMBL12497751 0.98 KDM4E (0.72) KDM4EMEN1ALDH1A1TYMSPOLB
Folic Acid SCHEMBL19837676 0.98 KDM4E (0.72) KDM4EMEN1ALDH1A1TYMSPOLB
Folic Acid SCHEMBL22441084 0.98 KDM4E (0.72) KDM4EMEN1ALDH1A1TYMSPOLB
Folic Acid SCHEMBL1887022 0.98 KDM4E (0.72) KDM4EMEN1ALDH1A1TYMSPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119523096-A Strong-absorption water-soluble fucoxanthin composite preparation and application thereof in uric acid-reducing functional food 集美大学 2025-02-28 CN claimed
CN-102765818-B Circulating water system is from draining reuse anti-incrustation corrosion inhibitor WUHAN RUNERHUA TECHNOLOGY CO., LTD. (CN) 2015-10-28 CN claimed
CN-102765819-B Self-draining water recycling process of water circulating system WUHAN RUNERHUA TECHNOLOGY CO LTD 2015-04-22 CN claimed
CN-102942571-A Process for preparing pistia stratiotes folic acid sodium salt UNIV XI AN ARCHITECTURE & TECH 2013-02-27 CN claimed
CN-102765819-A Self-draining water recycling process of water circulating system WUHAN RUNERHUA TECHNOLOGY CO LTD 2012-11-07 CN claimed
CN-102765818-A Corrosion and scale inhibitor special for recycling self-drained water of circulating water system WUHAN RUNERHUA TECHNOLOGY CO LTD 2012-11-07 CN claimed
CN-119523096-A Strong-absorption water-soluble fucoxanthin composite preparation and application thereof in uric acid-reducing functional food 集美大学 2025-02-28 CN disclosed
CN-119523096-A Strong-absorption water-soluble fucoxanthin composite preparation and application thereof in uric acid-reducing functional food 集美大学 2025-02-28 CN disclosed
CN-110201160-A The preparation method of zirconium metal organic framework compound 广东医科大学 2019-09-06 CN disclosed
CN-103271083-B Multi-functional ionic liquid compositions 阿拉巴马大学 2017-08-11 CN disclosed
CN-106110331-A Folate molecule target magnetic nano drug and preparation method thereof 骆子义 2016-11-16 CN disclosed
CN-102765818-B Circulating water system is from draining reuse anti-incrustation corrosion inhibitor WUHAN RUNERHUA TECHNOLOGY CO., LTD. (CN) 2015-10-28 CN disclosed
CN-102765819-B Self-draining water recycling process of water circulating system WUHAN RUNERHUA TECHNOLOGY CO LTD 2015-04-22 CN disclosed
WO-2004054936-A1 STABILIZED AQUEOUS FOLIC ACID PREPARATION AND PROCESS FOR PROVIDING THE SAME BLUM HOLGER (DE) 2004-07-01 WO disclosed
EP-0679081-B1 PHARMACEUTICAL COMPOSITIONS FOR PREVENTION AND TREATMENT OF CANCEROUS DISEASE AND PROCESS FOR THEIR PREPARATION IMMUNAL KFT (HU) 2002-02-06 EP disclosed
EP-0679081-A1 PHARMACEUTICAL COMPOSITIONS FOR PREVENTION AND TREATMENT OF CANCEROUS DISEASE AND PROCESS FOR THEIR PREPARATION IMMUNAL KFT (HU) 1995-11-02 EP disclosed
EP-0416232-B1 Stable injectable pharmaceutical formulation for folic acid and leucovorin salts and method AMERICAN CYANAMID CO (US) 1995-08-16 EP disclosed
WO-1995013061-A1 PHARMACEUTICAL COMPOSITIONS FOR PREVENTION AND TREATMENT OF CANCEROUS DISEASE AND PROCESS FOR THEIR PREPARATION IMMUNAL KFT. (HU) 1995-05-18 WO disclosed
US-5173488-A Tromethamine and monothioglycerol as buffers and antioxidants AMERICAN CYANAMID COMPANY (US) 1992-12-22 US disclosed
EP-0416232-A2 Stable injectable pharmaceutical formulation for folic acid and leucovorin salts and method AMERICAN CYANAMID COMPANY (US) 1991-03-13 EP disclosed