Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 17/20 | 0.72 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.72 |
| ▸ | SLC9A1 | P19634 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12189214 | 0.85 | CYP19A1 (0.71) | CYP19A1CYP11B1 | |
| SCHEMBL3873165 | 0.85 | CYP19A1 (0.71) | CYP19A1CYP11B1 | |
| SCHEMBL3872062 | 0.84 | CYP19A1 (0.66) | CYP19A1CYP11B1 | |
| Rac-Vorozole SCHEMBL29606650 | 0.84 | CYP19A1 (1.00) | CYP19A1CYP11B1 | |
| Vorozole SCHEMBL4554 | 0.84 | CYP19A1 (1.00) | CYP19A1CYP11B1 | |
| Rac-Vorozole SCHEMBL13223107 | 0.84 | CYP19A1 (1.00) | CYP19A1CYP11B1 | |
| Rac-Vorozole SCHEMBL1552681 | 0.84 | CYP19A1 (1.00) | CYP19A1CYP11B1 | |
| Vorozole SCHEMBL29363602 | 0.84 | CYP19A1 (1.00) | CYP19A1CYP11B1 | |
| [N-Methyl-11C]Vorozole SCHEMBL12171619 | 0.84 | CYP19A1 (1.00) | CYP19A1CYP11B1 | |
| SCHEMBL3873803 | 0.82 | CYP19A1 (0.67) | CYP19A1CYP11B1SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874304-B1 | BENZOTRIAZOLE DERIVATIVES AS CANNABINOID RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2009-07-15 | — | — | EP | claimed |
| US-20080194656-A1 | Benzotriazole Derivatives as Cannabinoid Receptor Antagonists | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-08-14 | — | — | US | disclosed |
| US-20080194656-A1 | Benzotriazole Derivatives as Cannabinoid Receptor Antagonists | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194656-A1 | Benzotriazole Derivatives as Cannabinoid Receptor Antagonists | CNR1, CNR2, HTR3C | CYP19A1 1108/4885CYP11B1 362/4885SLC9A1 1898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.