Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2249201 | 1.00 | FAAH (0.37) | FAAHAGTR2SMOCTSBCTSS | |
| SCHEMBL2244302 | 0.91 | SMN1; SMN2 (0.41) | FAAHSMOSMN1; SMN2CHRM4CHRM2 | |
| SCHEMBL2247701 | 0.89 | GAA (0.41) | FAAHAGTR2SMOCTSBCTSS | |
| SCHEMBL3867299 | 0.89 | HSD11B1 (0.40) | FAAHCTSBCTSSCTSKGAA | |
| SCHEMBL2246944 | 0.89 | MMP2 (0.46) | CTSBCTSSCTSKGAASMN1; SMN2 | |
| SCHEMBL2250358 | 0.89 | FAAH (0.48) | FAAHSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL2244549 | 0.89 | HSD11B1 (0.40) | FAAHCTSBCTSSCTSKGAA | |
| SCHEMBL2252429 | 0.88 | CHRM2 (0.47) | SMOCHRM4CHRM2CHRM1 | |
| SCHEMBL2245185 | 0.88 | CTSB (0.43) | FAAHCTSBCTSSCTSK | |
| SCHEMBL2252345 | 0.88 | FAAH (0.42) | FAAHSMOCHRM4CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771421-B1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | SERONO LAB (CH) | 2009-04-29 | — | — | EP | claimed |