SCHEMBL3879900

SCHEMBL3879900

CNC(F)(F)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 5/20 0.56
TSHR P16473 3/20 0.50
ALDH1A1 P00352 2/20 0.50
LMNA P02545 1/20 0.43
CYP2D6 P10635 1/20 0.43
PTPN1 P18031 1/20 0.39
MAPK1 P28482 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA5A P35218 1/20 0.38
CA9 Q16790 1/20 0.38
KIF11 P52732 1/20 0.37
TAAR1 Q96RJ0 2/20 0.36
ALOX15 P16050 1/20 0.36
ATM Q13315 1/20 0.36
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC2 Q92769 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24390041 0.79 KIF11 (0.52) TSHRALDH1A1MAPK1CA1CA2
SCHEMBL24724930 0.77 ACHE (0.46) KCNN4ALDH1A1LMNACYP2D6MAPK1
Trifluoromethylbenzene SCHEMBL1768875 0.76 TSHR (0.78) KCNN4TSHRALDH1A1LMNACYP2D6
SCHEMBL6399480 0.76 TSHR (0.52) KCNN4TSHRALDH1A1PTPN1MAPK1
SCHEMBL20487023 0.75 KCNN4 (0.31) KCNN4KIF11
SCHEMBL28382009 0.75 KCNN4 (0.52) KCNN4TSHRALDH1A1LMNACYP2D6
SCHEMBL4122475 0.74 TSHR (0.50) KCNN4TSHRALDH1A1LMNACYP2D6
SCHEMBL22200647 0.74 TSHR (0.50) KCNN4TSHRALDH1A1LMNAPTPN1
Hydrochloric Acid SCHEMBL4028283 0.73 KCNN4 (0.50) KCNN4TSHRALDH1A1LMNACYP2D6
SCHEMBL17586669 0.73 KCNN4 (0.50) KCNN4TSHRALDH1A1LMNACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1422216-B1 FLUORINE COMPOUND AND FLUORINATING AGENT COMPRISING THE COMPOUND MITSUBISHI GAS CHEMICAL CO (JP) 2009-01-07 EP disclosed