Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL822098 | 0.79 | ACHE (0.52) | ACHEPTPN5HTTCYP3A4CYP2D6 | |
| SCHEMBL148048 | 0.79 | NFE2L2 (0.55) | ACHEPTPN5HTTMEN1RAB9A | |
| SCHEMBL8242617 | 0.77 | ACHE (0.50) | ACHEPTPN5HTTCYP3A4CYP2D6 | |
| SCHEMBL18891585 | 0.77 | ACHE (0.50) | ACHEPTPN5HTTCYP3A4CYP2D6 | |
| Bromide SCHEMBL27462091 | 0.77 | NFE2L2 (0.53) | ACHEPTPN5HTTMEN1RAB9A | |
| Ammonia Solution, Strong SCHEMBL1869257 | 0.77 | NFE2L2 (0.53) | ACHEPTPN5HTTMEN1RAB9A | |
| SCHEMBL3879900 | 0.77 | KCNN4 (0.56) | CYP2D6LMNAKIF11KCNN4ALDH1A1 | |
| SCHEMBL27012754 | 0.76 | ACHE (0.48) | ACHEPTPN5HTTCYP3A4CYP2D6 | |
| SCHEMBL14463377 | 0.76 | ACHE (0.48) | ACHEPTPN5HTTCYP3A4CYP2D6 | |
| SCHEMBL3879898 | 0.76 | ACHE (0.48) | ACHEPTPN5HTTCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235699-A2 | POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |
| US-9610368-B2 | Radiolabelled glutaminyl cyclase (QC) inhibitors and uses of same | PROBIODRUG AG (DE) | 2017-04-04 | — | — | US | disclosed |