Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 5/20 | 0.59 |
| ▸ | DCUN1D1 | Q96GG9 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3880051 | 0.89 | L3MBTL1 (0.54) | UBE2MDCUN1D1LMNAMEN1KMT2A | |
| SCHEMBL3879360 | 0.89 | UBE2M (0.55) | UBE2MDCUN1D1LMNAMEN1KMT2A | |
| SCHEMBL3879014 | 0.87 | PROKR1 (0.44) | UBE2MDCUN1D1LMNAL3MBTL3L3MBTL1 | |
| SCHEMBL3882382 | 0.87 | L3MBTL3 (0.44) | UBE2MDCUN1D1LMNAMEN1KMT2A | |
| SCHEMBL3880257 | 0.85 | NPSR1 (0.49) | UBE2MDCUN1D1LMNAKMT2AL3MBTL1 | |
| SCHEMBL3879089 | 0.84 | KDM4E (0.51) | UBE2MDCUN1D1LMNAMEN1KMT2A | |
| SCHEMBL3877921 | 0.84 | GRM5 (0.46) | UBE2MDCUN1D1LMNAMEN1KMT2A | |
| SCHEMBL3881012 | 0.84 | MAPK1 (0.44) | UBE2MDCUN1D1MEN1KMT2AL3MBTL3 | |
| SCHEMBL3879400 | 0.84 | L3MBTL3 (0.40) | UBE2MDCUN1D1LMNAMEN1KMT2A | |
| SCHEMBL3880892 | 0.84 | UBE2M (0.57) | UBE2MDCUN1D1LMNAGRM5HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858900-B1 | FUSED THIAZOLE DERIVATIVES HAVING AFFINITY FOR THE HISTAMINE H3 RECEPTOR | GLAXO GROUP LTD (GB) | 2009-01-07 | — | — | EP | claimed |
| EP-1858900-B1 | FUSED THIAZOLE DERIVATIVES HAVING AFFINITY FOR THE HISTAMINE H3 RECEPTOR | GLAXO GROUP LTD (GB) | 2009-01-07 | — | — | EP | disclosed |