Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.65 |
| ▸ | PRKACA | P17612 | 3/20 | 0.65 |
| ▸ | PRKACG | P22612 | 3/20 | 0.65 |
| ▸ | PRKACB | P22694 | 3/20 | 0.65 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.38 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.38 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.38 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.38 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.38 |
| ▸ | ATP1B3 | P54709 | 2/20 | 0.38 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.38 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 2/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980308 | 0.80 | SRC (1.00) | SRCPRKACAPRKACGPRKACBAR | |
| SCHEMBL1887694 | 0.80 | SRC (0.61) | SRCPRKACAPRKACGPRKACBCA1 | |
| SCHEMBL30143007 | 0.80 | SRC (0.61) | SRCPRKACAPRKACGPRKACBCA1 | |
| SCHEMBL3874796 | 0.74 | SRC (0.41) | SRCPRKACAPRKACGPRKACBAR | |
| SCHEMBL3877130 | 0.74 | SRC (0.41) | SRCPRKACAPRKACGPRKACBAR | |
| Acetone SCHEMBL8600747 | 0.73 | APP (0.55) | SRCPRKACAPRKACGPRKACBPIM1 | |
| SCHEMBL20356047 | 0.72 | HIF1A (0.54) | SRCPRKACAPRKACGPRKACBATP1A1 | |
| SCHEMBL16641054 | 0.69 | HIF1A (0.52) | SRCPRKACAPRKACGPRKACBATP1A1 | |
| SCHEMBL338346 | 0.67 | ALDH1A1 (0.57) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL29373601 | 0.67 | ALDH1A1 (0.57) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080098535-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof | GLENN ROBERT W JR | 2008-05-01 | — | — | US | claimed |
| US-20050217038-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-10-06 | — | — | US | claimed |
| US-7491245-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2009-02-17 | — | — | US | disclosed |
| US-20080098535-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof | GLENN ROBERT W JR | 2008-05-01 | — | — | US | disclosed |
| US-7331997-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-02-19 | — | — | US | disclosed |
| EP-1735059-A2 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | The Procter and Gamble Company (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005099656-A2 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2005-10-27 | — | — | WO | disclosed |
| US-20050217038-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050217038-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, CKMT1A; CKMT1B, TUBB6 | SRC 2779/4885PRKACA 1460/4885PRKACG 1247/4885 |
| US-20080098535-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof | KRT18, CKMT1A; CKMT1B, TUBB6 | SRC 2779/4885PRKACA 1460/4885PRKACG 1247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.