Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.34 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3882575 | 0.99 | PTGS2 (0.43) | PTGS2ARAPPENPP2EPHX1 | |
| SCHEMBL3882470 | 0.89 | PTGS2 (0.41) | PTGS2ARENPP2SMYD3MET | |
| SCHEMBL3897348 | 0.89 | PTGS2 (0.41) | PTGS2ARAPPENPP2MCL1 | |
| SCHEMBL3882109 | 0.86 | PTGS2 (0.41) | PTGS2ARAPPENPP2EPHX1 | |
| SCHEMBL3883960 | 0.86 | FFAR4 (0.39) | PTGS2APPPTGS1 | |
| SCHEMBL3884624 | 0.85 | PTGS2 (0.40) | PTGS2APPENPP2EPHX1PARP10 | |
| SCHEMBL3884011 | 0.85 | APP (0.41) | PTGS2APPPTGS1 | |
| SCHEMBL3680532 | 0.85 | THRA (0.48) | PTGS2ARENPP2EPHX1PI4K2A | |
| SCHEMBL3883630 | 0.84 | THRA (0.50) | PTGS2ARENPP2EPHX1PI4K2A | |
| SCHEMBL3882042 | 0.84 | PTGS2 (0.43) | PTGS2ENPP2EPHX1MAP3K11CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |