Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3883758 | 0.90 | PTGS2 (0.41) | PTGS2MTORMCL1MAP3K11THRA | |
| SCHEMBL3891613 | 0.90 | APP (0.42) | PTGS2MTORMCL1MAP3K11THRA | |
| SCHEMBL3882901 | 0.89 | PTGS2 (0.43) | PTGS2ARMCL1MAP3K11ENPP2 | |
| SCHEMBL3882575 | 0.88 | PTGS2 (0.43) | PTGS2ARMCL1MAP3K11THRA | |
| SCHEMBL3893664 | 0.87 | PTGS2 (0.39) | PTGS2MTORMCL1MAP3K11THRA | |
| SCHEMBL3892394 | 0.86 | AKR1C3 (0.38) | THRATHRBAPPFABP4 | |
| SCHEMBL3884668 | 0.86 | PTGS2 (0.42) | PTGS2MTORMAP3K11ENPP2VCP | |
| SCHEMBL3483255 | 0.86 | THRA (0.49) | PTGS2MTORTHRATHRBENPP2 | |
| SCHEMBL3882329 | 0.83 | THRA (0.38) | PTGS2MTORARTHRATHRB | |
| SCHEMBL3888016 | 0.83 | PTGS2 (0.43) | PTGS2MTORARMCL1MAP3K11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |