Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3880893 | 0.89 | FFAR1 (0.44) | AKR1C3AKR1C2ADAMTS4MMP13FFAR1 | |
| SCHEMBL3954848 | 0.87 | AKR1C3 (0.47) | AKR1C3AKR1C2PSEN1PSEN2APH1B | |
| SCHEMBL3885770 | 0.86 | PTGES (0.43) | AKR1C3AKR1C2PSEN1PSEN2APH1B | |
| SCHEMBL3881440 | 0.86 | PTGS2 (0.40) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL3881786 | 0.85 | FFAR1 (0.52) | RXRARXRBRXRGFFAR1PPARD | |
| SCHEMBL3881631 | 0.83 | CCNC (0.45) | PSEN1CXCR2RXRARXRBRXRG | |
| SCHEMBL3886441 | 0.81 | AKR1C3 (0.40) | AKR1C3AKR1C2ADAMTS4MMP13FFAR1 | |
| SCHEMBL3885070 | 0.81 | AKR1C3 (0.40) | AKR1C3AKR1C2FFAR1PTGER1PTGER4 | |
| SCHEMBL3883495 | 0.81 | PLA2G10 (0.40) | AKR1C3AKR1C2FFAR1PTGER1PTGER4 | |
| SCHEMBL3882342 | 0.80 | PPARG (0.39) | AKR1C3AKR1C2FFAR1S1PR5PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |