SCHEMBL3883072

SCHEMBL3883072

C=C1CCC(C(=O)CS(=O)(=O)c2ccc(OCc3cc(C)cc(OC)c3)cc2)CC1

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 14/20 0.47
SPHK1 Q9NYA1 3/20 0.39
PARP10 Q53GL7 1/20 0.38
SPHK2 Q9NRA0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3880971 0.93 PARP10 (0.44) FFAR1PARP10
SCHEMBL3882358 0.85 MMP2 (0.45) FFAR1
SCHEMBL3880178 0.83 FFAR1 (0.42) FFAR1SPHK1
SCHEMBL3889770 0.82 MMP2 (0.44) FFAR1SPHK1PARP10SPHK2
SCHEMBL3881640 0.80 ADAM17 (0.43) FFAR1SPHK1SPHK2
SCHEMBL3887431 0.78 FFAR1 (0.36) FFAR1SPHK1PARP10
SCHEMBL3887435 0.78 FFAR1 (0.36) FFAR1SPHK1PARP10
SCHEMBL3880990 0.77 MMP2 (0.63) FFAR1
SCHEMBL3884532 0.74 ADAM17 (0.64)
SCHEMBL3880883 0.74 MMP13 (0.47) FFAR1SPHK1PARP10SPHK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7511144-B2 Reverse hydroxamic acid derivatives KAKEN PHARMACEUTICAL CO., LTD. (JP) 2009-03-31 US disclosed
EP-1431285-B1 REVERSE HYDROXAMIC ACID DERIVATIVES KAKEN PHARMA CO LTD (JP) 2009-01-07 EP disclosed
US-20040242928-A1 Tumor necrosis factor converting enzyme inhibitor; antiarthritic agents; lupus; Crohn's disease; multiple sclerosis; antidiabetic agents; infections;; asthma; skin disorders; anemia STUDOR S.A. (LU) 2004-12-02 US disclosed
EP-1431285-A1 REVERSE HYDROXAMIC ACID DERIVATIVES Kaken Pharmaceutical Co., Ltd. (JP) 2004-06-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040242928-A1 Tumor necrosis factor converting enzyme inhibitor; antiarthritic agents; lupus; Crohn's disease; multiple sclerosis; antidiabetic agents; infections;; asthma; skin disorders; anemia TNF, RNASE1, IFNAR1 FFAR1 239/4885SPHK1 2189/4885PARP10 2037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.