Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9793625 | 0.84 | S100A4 (0.41) | TSHRMAP2K7S100A4CDC25ACDC25B | |
| SCHEMBL29738631 | 0.82 | HTR7 (0.48) | MCHR1TSHRACHERAB9AMAPT | |
| SCHEMBL28367443 | 0.82 | MCHR1 (0.48) | MCHR1TSHRACHERAB9AMAPT | |
| SCHEMBL9770355 | 0.82 | HTR7 (0.48) | MCHR1TSHRACHERAB9AMAPT | |
| SCHEMBL10144088 | 0.81 | PTGS2 (0.49) | MCHR1TSHRACHERAB9AMAPT | |
| SCHEMBL16347586 | 0.78 | MCHR1 (0.46) | MCHR1TSHRACHERAB9AMAPT | |
| SCHEMBL5170853 | 0.78 | HTR7 (0.46) | MCHR1TSHRACHERAB9AMAPT | |
| SCHEMBL27631808 | 0.78 | MCHR1 (0.46) | MCHR1TSHRACHERAB9AMAPT | |
| SCHEMBL5517749 | 0.78 | MCHR1 (0.46) | MCHR1TSHRACHERAB9AMAPT | |
| SCHEMBL6734336 | 0.78 | CD44 (0.46) | TSHRMAP2K7S100A4CDC25ACDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118948925-A | A composition extracted from Celastrus orbiculatus plant for treating cancer, and its preparation method and application | 广西仙手棋药业科技有限公司 | 2024-11-15 | — | — | CN | claimed |
| CN-117959276-A | A composition extracted from Celastrus orbiculatus plant for treating cancer, and its preparation method and application | 广西仙手棋药业科技有限公司 | 2024-05-03 | — | — | CN | claimed |
| US-12565497-B2 | Sulfone derivatives | HOFFMANN-LA ROCHE INC. (US) | 2026-03-03 | — | — | US | disclosed |
| CN-118948925-A | A composition extracted from Celastrus orbiculatus plant for treating cancer, and its preparation method and application | 广西仙手棋药业科技有限公司 | 2024-11-15 | — | — | CN | disclosed |
| US-12100809-B2 | Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery | MITSUBISHI CHEMICAL CORPORATION (JP) | 2024-09-24 | — | — | US | disclosed |
| US-20240297344-A1 | NONAQUEOUS ELECTROLYTE FOR SECONDARY BATTERY AND NONAQUEOUS-ELECTROLYTE SECONDARY BATTERY EMPLOYING THE SAME | MITSUBISHI CHEMICAL CORPORATION (JP) | 2024-09-05 | — | — | US | disclosed |
| CN-114685331-B | Process for producing 1, 2-dithioethane compound | 华南理工大学 | 2024-07-09 | — | — | CN | disclosed |
| CN-117959276-A | A composition extracted from Celastrus orbiculatus plant for treating cancer, and its preparation method and application | 广西仙手棋药业科技有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-117567331-A | Synthesis method of 1, 2-dithioethane compound and 1, 4-dithiane | 河北北方学院 | 2024-02-20 | — | — | CN | disclosed |
| EP-3835290-B1 | OXADIAZOLINE COMPOUND OR SALT THEREOF, AGRICULTURAL OR HORTICULTURAL BACTERICIDE CONTAINING SAID COMPOUND, AND USE METHOD THEREFOR | NIHON NOHYAKU CO LTD (JP) | 2023-09-06 | — | — | EP | disclosed |
| WO-2023144793-A1 | POL THETA INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2023-08-03 | — | — | WO | disclosed |
| WO-1998005721-A1 | POLYESTER BASED OPTICAL FIBER COATINGS | ALLIEDSIGNAL INC. (US) | 1998-02-12 | — | — | WO | disclosed |
| US-5672675-A | Vinyl ether-terminated polyester oligomer stabilizers for vinyl ether-based coating systems | ALLIEDSIGNAL, INC. (US) | 1997-09-30 | — | — | US | disclosed |
| US-5514727-A | OPTICAL FIBER COATINGS, POLYETHER OR POLYESTER POLYOLS ENDCAPPED WITH HYDROXY VINYL ETHER | ALLIEDSIGNAL INC. (US) | 1996-05-07 | — | — | US | disclosed |
| WO-1996006142-A1 | POLYESTER BASED OPTICAL FIBER COATINGS | ALLIEDSIGNAL INC. (US) | 1996-02-29 | — | — | WO | disclosed |
| EP-0191496-B1 | TRIAZINE DERIVATIVES, A PROCESS FOR PREPARING THE DERIVATIVES, AND HERBICIDES CONTAINING THE DERIVATIVES AS THE EFFECTIVE COMPONENT | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4680054-A | Triazine derivatives, a process for preparing the derivatives, and herbicides containing the derivatives as the effective component | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1987-07-14 | — | — | US | disclosed |
| EP-0191496-A2 | Triazine Derivatives, a process for preparing the derivatives, and herbicides containing the derivatives as the effective component | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1986-08-20 | — | — | EP | disclosed |
| US-4339611-A | BUTANOL, BUTANAL, COBALT, IODINE | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-07-13 | — | — | US | disclosed |
| US-3954871-A | ANTIARRHYTHMIA, VASODILATOR, HYPOTENSIVE | CONTINENTAL PHARMA (BE) | 1976-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12565497-B2 | Sulfone derivatives | CXCR1, CCR1, SULT1E1 | MCHR1 930/4885TSHR 1132/4885ACHE 4324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.