Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CETP | P11597 | 2/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | UBE2N | P61088 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4807354 | 1.00 | TSHR (0.33) | TSHRTDP1CYP2D6CETPSPHK1 | |
| SCHEMBL4807351 | 1.00 | TSHR (0.33) | TSHRTDP1CYP2D6CETPSPHK1 | |
| SCHEMBL13395753 | 1.00 | TSHR (0.33) | TSHRTDP1CYP2D6CETPSPHK1 | |
| Hydrochloric Acid SCHEMBL3171229 | 0.97 | TSHR (0.32) | TSHRTDP1CYP2D6CETPSPHK1 | |
| SCHEMBL13395751 | 0.76 | — | — | |
| SCHEMBL13395698 | 0.76 | — | — | |
| SCHEMBL13395755 | 0.72 | TSHR (0.37) | TSHRTDP1 | |
| SCHEMBL13395757 | 0.72 | TSHR (0.37) | TSHRTDP1 | |
| SCHEMBL2888442 | 0.72 | CETP (0.33) | CETP | |
| SCHEMBL13395730 | 0.72 | TSHR (0.37) | TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7737303-B2 | Production of chirally pure amino alcohol intermediates, derivatives thereof, and uses thereof | WYETH LLC (US) | 2010-06-15 | — | — | US | disclosed |
| US-7737303-B2 | Production of chirally pure amino alcohol intermediates, derivatives thereof, and uses thereof | WYETH LLC (US) | 2010-06-15 | — | — | US | disclosed |
| US-7598422-B2 | Production of chirally pure amino alcohol intermediates, derivatives thereof, and uses thereof | WYETH (US) | 2009-10-06 | — | — | US | disclosed |
| US-7598422-B2 | Production of chirally pure amino alcohol intermediates, derivatives thereof, and uses thereof | WYETH (US) | 2009-10-06 | — | — | US | disclosed |
| EP-2010478-A1 | PRODUCTION OF CHIRALLY PURE AMINO ALCOHOL INTERMEDIATES, DERIVATIVES THEREOF, AND USES THEREOF | Wyeth (US) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007127108-A1 | PRODUCTION OF CHIRALLY PURE AMINO ALCOHOL INTERMEDIATES, DERIVATIVES THEREOF, AND USES THEREOF | WYETH (US) | 2007-11-08 | — | — | WO | disclosed |
| US-20070249869-A1 | Production of chirally pure amino alcohol intermediates, derivatives thereof, and uses thereof | WYETH (US) | 2007-10-25 | — | — | US | disclosed |
| US-20070249869-A1 | Production of chirally pure amino alcohol intermediates, derivatives thereof, and uses thereof | WYETH (US) | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249869-A1 | Production of chirally pure amino alcohol intermediates, derivatives thereof, and uses thereof | ADH1C, ADH1A, ACMSD | TSHR 1058/4885TDP1 2042/4885CYP2D6 1969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.