Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 2/20 | 0.38 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | TPH1 | P17752 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | DDR2 | Q16832 | 3/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3891048 | 0.93 | MAPK14 (0.41) | BCL9CTNNB1CTSCF11FGFR1 | |
| SCHEMBL3889253 | 0.92 | MAPK14 (0.40) | BCL9CTNNB1CTSCF11FGFR1 | |
| SCHEMBL3881923 | 0.92 | MAPK14 (0.40) | BCL9CTNNB1CTSCF11FGFR1 | |
| SCHEMBL3883049 | 0.84 | FFAR4 (0.48) | BCL9CTNNB1CTSCFGFR1FGFR2 | |
| SCHEMBL3892376 | 0.84 | PDE4A (0.43) | TPH1ADRB1ADRB3PDE4APDE4B | |
| SCHEMBL3884512 | 0.83 | IKBKB (0.44) | ADRB1ADRB3KMOPDE4A | |
| SCHEMBL3887129 | 0.83 | ADRB1 (0.44) | TPH1ADRB1ADRB3KMOPDE4A | |
| SCHEMBL3893626 | 0.83 | IKBKB (0.43) | ADRB1ADRB3KMOPDE4A | |
| SCHEMBL3885133 | 0.83 | FFAR4 (0.44) | CTSCTPH1ADRB1ADRB3KMO | |
| SCHEMBL3883962 | 0.81 | PDE4A (0.38) | ABL1PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |