Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 11/20 | 0.44 |
| ▸ | CHUK | O15111 | 9/20 | 0.44 |
| ▸ | LCK | P06239 | 2/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 5/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3893626 | 0.99 | IKBKB (0.43) | IKBKBCHUKLCKROCK1ADRB1 | |
| SCHEMBL3895963 | 0.88 | IKBKB (0.42) | IKBKBCHUKLCKROCK1FFAR4 | |
| SCHEMBL3892376 | 0.88 | PDE4A (0.43) | ADRB1ADRB3FFAR4PDE4A | |
| SCHEMBL3887129 | 0.87 | ADRB1 (0.44) | ADRB1ADRB3FFAR4PDE4AKMO | |
| SCHEMBL3883590 | 0.84 | FFAR4 (0.53) | IKBKBCHUKLCKROCK1ADRB1 | |
| SCHEMBL3883580 | 0.83 | BCL9 (0.40) | ADRB1ADRB3PDE4AKMO | |
| SCHEMBL3891048 | 0.83 | MAPK14 (0.41) | ROCK1 | |
| SCHEMBL3884680 | 0.83 | FFAR4 (0.52) | IKBKBCHUKLCKROCK1ADRB1 | |
| SCHEMBL3885362 | 0.83 | S1PR1 (0.37) | ADRB1ADRB3FFAR4PDE4AKMO | |
| SCHEMBL3889253 | 0.83 | MAPK14 (0.40) | ROCK1ADRB1ADRB3KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |