Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 3/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.44 |
| ▸ | PDE4A | P27815 | 5/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.41 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.41 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.41 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.41 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.41 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.41 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.41 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3892376 | 0.99 | PDE4A (0.43) | ADRB1ADRB3PDE4APLA2G10PLA2G2A | |
| SCHEMBL3893626 | 0.88 | IKBKB (0.43) | ADRB1ADRB3PDE4AFFAR4KMO | |
| SCHEMBL3884512 | 0.87 | IKBKB (0.44) | ADRB1ADRB3PDE4AFFAR4KMO | |
| SCHEMBL3883671 | 0.85 | PTGS2 (0.43) | ADRB1ADRB3PDE4AAPPPDE4B | |
| SCHEMBL3882409 | 0.85 | PTGER1 (0.42) | PLA2G10PLA2G2APLA2G1BPLA2G5PLA2G2C | |
| SCHEMBL3886327 | 0.85 | PPARG (0.50) | PLA2G10PLA2G2APLA2G1BPLA2G5PLA2G2C | |
| SCHEMBL3882042 | 0.84 | PTGS2 (0.43) | ADRB1ADRB3PDE4APLA2G10PLA2G2A | |
| SCHEMBL3881923 | 0.84 | MAPK14 (0.40) | ADRB1ADRB3KMOTPH1 | |
| SCHEMBL3889253 | 0.84 | MAPK14 (0.40) | ADRB1ADRB3KMOTPH1 | |
| SCHEMBL3888282 | 0.84 | GRM2 (0.39) | ADRB1ADRB3PDE4AAPPITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |