Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | CPT2 | P23786 | 1/20 | 0.38 |
| ▸ | CPT1A | P50416 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.38 |
| ▸ | XDH | P47989 | 3/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3891048 | 0.88 | MAPK14 (0.41) | F11MAPK14CPT2CPT1ATRPA1 | |
| SCHEMBL3881923 | 0.88 | MAPK14 (0.40) | F11MAPK14CPT2CPT1ATRPA1 | |
| SCHEMBL3889253 | 0.88 | MAPK14 (0.40) | F11MAPK14CPT2CPT1ATRPA1 | |
| SCHEMBL3884668 | 0.86 | PTGS2 (0.42) | MTORXDH | |
| SCHEMBL3883888 | 0.85 | THRA (0.44) | F11MAPK14CPT2CPT1APIK3CA | |
| SCHEMBL3882442 | 0.84 | THRA (0.46) | F11MAPK14CPT2CPT1APIK3CA | |
| SCHEMBL3884956 | 0.83 | HPGD (0.39) | XDHTRPV1P2RX3 | |
| SCHEMBL3882409 | 0.83 | PTGER1 (0.42) | — | |
| SCHEMBL3892440 | 0.83 | TRPA1 (0.42) | TRPA1AURKADAPK3JAK2ROCK2 | |
| SCHEMBL3884976 | 0.83 | PPARG (0.40) | MTORXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |