Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.44 |
| ▸ | PPARA | Q07869 | 11/20 | 0.44 |
| ▸ | PPARD | Q03181 | 7/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3884528 | 0.91 | PPARG (0.46) | PPARGPPARAPPARD | |
| SCHEMBL3882927 | 0.85 | PPARG (0.44) | PPARGPPARAPPARD | |
| SCHEMBL3884521 | 0.83 | THRA (0.48) | PPARAPPARDELANEDHODHPARP15 | |
| SCHEMBL3882775 | 0.80 | ELANE (0.42) | PPARDELANEDHODHPARP15PARP10 | |
| SCHEMBL3888367 | 0.79 | PDE4B (0.44) | PPARGPPARAPPARD | |
| SCHEMBL3882136 | 0.79 | PPARG (0.41) | PPARGPPARAPPARD | |
| SCHEMBL3881996 | 0.79 | KEAP1 (0.40) | PPARGPPARAPPARD | |
| SCHEMBL3884992 | 0.79 | PPARG (0.40) | PPARGPPARAPPARD | |
| SCHEMBL3882409 | 0.79 | PTGER1 (0.42) | PPARGPPARAPPARDAKR1C3AKR1C2 | |
| SCHEMBL3889302 | 0.78 | PPARG (0.46) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |