Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.46 |
| ▸ | PPARA | Q07869 | 12/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3884528 | 0.85 | PPARG (0.46) | PPARGPPARAPPARDPLA2G10PLA2G2A | |
| SCHEMBL3682530 | 0.82 | THRA (0.48) | PTGER1 | |
| SCHEMBL5798987 | 0.81 | PTGER1 (0.41) | PTGER1 | |
| SCHEMBL3685610 | 0.80 | PTGER1 (0.44) | PTGER1 | |
| SCHEMBL3883672 | 0.78 | PPARG (0.44) | PPARGPPARAPPARD | |
| SCHEMBL3882927 | 0.78 | PPARG (0.44) | PPARGPPARAPPARDPLA2G10PLA2G2A | |
| SCHEMBL3886879 | 0.75 | BRD4 (0.42) | PTGER1 | |
| SCHEMBL3883437 | 0.74 | PTGER1 (0.44) | PTGER1 | |
| SCHEMBL3888367 | 0.74 | PDE4B (0.44) | PPARGPPARAPPARD | |
| SCHEMBL3883120 | 0.73 | BRD4 (0.42) | PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |