Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3481436 | 0.97 | NOTUM (0.39) | NOTUMMDM2 | |
| SCHEMBL3482166 | 0.84 | NOTUM (0.42) | NOTUM | |
| SCHEMBL501984 | 0.84 | NOTUM (0.42) | NOTUM | |
| SCHEMBL501983 | 0.84 | NOTUM (0.42) | NOTUM | |
| SCHEMBL502154 | 0.81 | NOTUM (0.41) | NOTUM | |
| SCHEMBL3835696 | 0.81 | NOTUM (0.41) | NOTUM | |
| SCHEMBL502155 | 0.81 | NOTUM (0.41) | NOTUM | |
| SCHEMBL3481434 | 0.81 | NOTUM (0.41) | NOTUM | |
| SCHEMBL4072255 | 0.80 | MEN1 (0.37) | — | |
| SCHEMBL5727680 | 0.79 | MGLL (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2019593-A1 | PRO-DRUGS OF TERTIARY ALCOHOLS | Merck & Co., Inc. (US) | 2009-02-04 | — | — | EP | disclosed |
| WO-2007136571-A1 | PRO-DRUGS OF TERTIARY ALCOHOLS | MERCK & CO., INC. (US) | 2007-11-29 | — | — | WO | disclosed |