Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | PAM | P19021 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3884865 | 1.00 | RAB9A (0.47) | RAB9AKDM4EALDH1A1PRMT1MAOB | |
| (Z)-1,2-Diphenylethene SCHEMBL11896257 | 0.90 | ALDH1A1 (0.44) | RAB9AKDM4EALDH1A1MAOBMEN1 | |
| SCHEMBL2770961 | 0.89 | KDM4E (0.55) | RAB9AKDM4EALDH1A1PRMT1MAOB | |
| SCHEMBL2770965 | 0.89 | KDM4E (0.55) | RAB9AKDM4EALDH1A1PRMT1MAOB | |
| SCHEMBL11200701 | 0.83 | ADRB2 (0.42) | RAB9AKDM4EPRMT1MAOBIDO1 | |
| SCHEMBL4356479 | 0.82 | RAB9A (0.49) | RAB9AKDM4EALDH1A1PRMT1MAOB | |
| SCHEMBL4356484 | 0.82 | RAB9A (0.49) | RAB9AKDM4EALDH1A1PRMT1MAOB | |
| SCHEMBL11597360 | 0.81 | PRMT1 (0.55) | RAB9AKDM4EALDH1A1PRMT1MAOB | |
| SCHEMBL14275030 | 0.81 | KDM4E (0.52) | RAB9AKDM4EALDH1A1PRMT1MAOB | |
| Styrene SCHEMBL608141 | 0.81 | ALDH1A1 (0.64) | RAB9AKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150175727-A1 | CYCLOPROPENIUM POLYMERS AND METHODS FOR MAKING THE SAME | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2015-06-25 | — | — | US | claimed |
| WO-2014022365-A1 | CYCLOPROPENIUM POLYMERS AND METHODS FOR MAKING THE SAME | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2014-02-06 | — | — | WO | claimed |
| US-10385150-B2 | Cyclopropenium polymers and methods for making the same | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2019-08-20 | — | — | US | disclosed |
| US-20180215847-A1 | CYCLOPROPENIUM POLYMERS AND METHODS FOR MAKING THE SAME | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2018-08-02 | — | — | US | disclosed |
| CN-107325123-A | Polyhedral oligomeric silsesquioxane containing multiple alkenyl or alkynyls and preparation method thereof | 北京化工大学 | 2017-11-07 | — | — | CN | disclosed |
| US-9758606-B2 | Cyclopropenium polymers and methods for making the same | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-09-12 | — | — | US | disclosed |
| US-20150175727-A1 | CYCLOPROPENIUM POLYMERS AND METHODS FOR MAKING THE SAME | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2015-06-25 | — | — | US | disclosed |
| WO-2014022365-A1 | CYCLOPROPENIUM POLYMERS AND METHODS FOR MAKING THE SAME | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2014-02-06 | — | — | WO | disclosed |
| US-8193391-B2 | Process for preparation of 3-(2-hydroxy-5-substituted phenyl)-N-alkyl-3-phenylpropylamines | LEK PHARMACEUTICALS, D.D. (SI) | 2012-06-05 | — | — | US | disclosed |
| US-7550500-B2 | Bicyclic and tricyclic amines as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-06-23 | — | — | US | disclosed |
| EP-2044001-A1 | PROCESS FOR PREPARATION OF 3-(2-HYDROXY-5-SUBSTITUTED PHENYL)-N-ALKYL-3-PHENYLPROPYLAMINES | Lek Pharmaceuticals D.D. (SI) | 2009-04-08 | — | — | EP | disclosed |
| EP-0646110-A1 | N-SUBSTITUED 3-AZABICYCLO 3.2.0]HEPTANE DERIVATIVES USEFUL AS NEUROLEPTIC AGENTS ETC. | BASF AG (DE) | 1995-04-05 | — | — | EP | disclosed |
| CN-1087341-A | The assorted norbornane derivative of the ammonia that N-replaces, preparation and its purposes | BASF AG (DE) | 1994-06-01 | — | — | CN | disclosed |
| WO-1994000431-A1 | N-SUBSTITUED 3-AZABICYCLO[3.2.0]HEPTANE DERIVATIVES USEFUL AS NEUROLEPTIC AGENTS ETC. | BASF AKTIENGESELLSCHAFT (DE) | 1994-01-06 | — | — | WO | disclosed |
| WO-1994000445-A1 | SUBSTITUED 3-AZABICYCLO[3.2.0]HEPTANE DERIVATES USEFUL AS INTERMEDIATE PRODUCTS | BASF AKTIENGESELLSCHAFT (DE) | 1994-01-06 | — | — | WO | disclosed |
| WO-1994000458-A1 | N-SUBSTITUTED 3-AZABICYCLO[3.2.0]HEPTANE DERIVATES USEFUL AS NEUROLEPTIC AGENTS, ETC. | BASF AKTIENGESELLSCHAFT (DE) | 1994-01-06 | — | — | WO | disclosed |
| US-4960797-A | Improving mood element, stimulating sexual activity of aged people; free of side effects | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1990-10-02 | — | — | US | disclosed |
| EP-0186680-B1 | PHENYLISOPROPYLAMINE DERIVATIVE AND ITS PREPARATION | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1988-03-30 | — | — | EP | disclosed |
| EP-0186680-A1 | PHENYLISOPROPYLAMINE DERIVATIVE AND ITS PREPARATION. | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1986-07-09 | — | — | EP | disclosed |
| WO-1985005617-A1 | PHENYLISOPROPYLAMINE DERIVATIVE AND ITS PREPARATION | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) | 1985-12-19 | — | — | WO | disclosed |