Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 3/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 3/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | TPH1 | P17752 | 2/20 | 0.36 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3882042 | 0.99 | PTGS2 (0.43) | PTGS2ADRB1ADRB3BRD4ENPP2 | |
| SCHEMBL3882128 | 0.88 | ROCK1 (0.41) | ADRB1ADRB3BRD4PDE4B | |
| SCHEMBL3884668 | 0.88 | PTGS2 (0.42) | PTGS2ENPP2C5AR1MAP3K11VCP | |
| SCHEMBL3887129 | 0.85 | ADRB1 (0.44) | ADRB1ADRB3KMOPDE4APDE4B | |
| SCHEMBL3889253 | 0.85 | MAPK14 (0.40) | ADRB1ADRB3KMOTPH1 | |
| SCHEMBL3881923 | 0.85 | MAPK14 (0.40) | ADRB1ADRB3KMOTPH1 | |
| SCHEMBL3882575 | 0.84 | PTGS2 (0.43) | PTGS2ENPP2EPHX1C5AR1APP | |
| SCHEMBL3892376 | 0.84 | PDE4A (0.43) | ADRB1ADRB3PDE4APDE4BPDE4C | |
| SCHEMBL3891048 | 0.84 | MAPK14 (0.41) | TPH1 | |
| SCHEMBL3882882 | 0.83 | FFAR4 (0.49) | ENPP2KMOEPHX1PDE4BVCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |