SCHEMBL3888955

SCHEMBL3888955

O=C(NC(Cc1ccccc1)C(=O)O)c1cc(=O)[nH]c(=O)[nH]1

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PYGL P06737 2/20 0.59
GPR84 Q9NQS5 1/20 0.56
ALB P02768 4/20 0.53
IL2 P60568 4/20 0.53
CCKAR P32238 1/20 0.53
CCKBR P32239 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.51
KDM4E B2RXH2 1/20 0.51
ALDH1A1 P00352 1/20 0.51
PKM P14618 1/20 0.51
ACE P12821 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3435215 0.88 ACE (0.56) PYGLGPR84KDM4EALDH1A1PKM
SCHEMBL3434998 0.83 GPR84 (0.45) PYGLGPR84ALBIL2CCKAR
SCHEMBL21185729 0.81 ALDH1A1 (0.49) PYGLGPR84ALBIL2ALDH1A1
SCHEMBL7971407 0.79 CCKAR (0.79) PYGLALBIL2CCKARCCKBR
SCHEMBL3360046 0.78 GRN (0.51) GPR84KDM4EALDH1A1
SCHEMBL21185586 0.78 KDM4E (0.47) GPR84CCKBRKDM4EALDH1A1
SCHEMBL28577021 0.78 KDM4E (0.47) GPR84CCKBRKDM4EALDH1A1
Hydrochloric Acid SCHEMBL28578292 0.77 KDM4E (0.46) GPR84CCKBRKDM4EALDH1A1
SCHEMBL1828604 0.77 PTPN1 (0.56) PYGLCCKARCCKBRL3MBTL1ACE
SCHEMBL21185465 0.77 ALDH1A1 (0.39) PYGLGPR84ALBIL2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8236952-B2 Preparations containing amino acids and orotic acid Northern Innovations Holding Corp. (CA) 2012-08-07 US disclosed
US-8236952-B2 Preparations containing amino acids and orotic acid Northern Innovations Holding Corp. (CA) 2012-08-07 US disclosed
US-8236952-B2 Preparations containing amino acids and orotic acid Northern Innovations Holding Corp. (CA) 2012-08-07 US disclosed
WO-2009076743-A1 PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID IOVATE T. & P. INC. (CA) 2009-06-25 WO disclosed
US-20090156812-A1 PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID IOVATE T. & P. INC. (CA) 2009-06-18 US disclosed
US-20090156812-A1 PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID IOVATE T. & P. INC. (CA) 2009-06-18 US disclosed
US-20090156812-A1 PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID IOVATE T. & P. INC. (CA) 2009-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090156812-A1 PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID DDC, ODC1, OTC PYGL 979/4885GPR84 3114/4885ALB 127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.