Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 3/20 | 0.51 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3433459 | 0.84 | GPR84 (0.41) | GRNSORT1ALDH1A1KMT2AKDM4E | |
| SCHEMBL21185729 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KMT2AGPR84LMNACYP1A2 | |
| SCHEMBL11979054 | 0.81 | LMNA (0.53) | ALDH1A1KMT2AKDM4EGPR84LMNA | |
| SCHEMBL28577021 | 0.81 | KDM4E (0.47) | ALDH1A1KDM4EGPR84LMNACYP1A2 | |
| SCHEMBL21185586 | 0.81 | KDM4E (0.47) | ALDH1A1KDM4EGPR84LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL28578292 | 0.80 | KDM4E (0.46) | ALDH1A1KDM4EGPR84LMNACYP1A2 | |
| SCHEMBL3433136 | 0.77 | GPR84 (0.49) | ALDH1A1KMT2AGPR84LMNACYP1A2 | |
| SCHEMBL25197064 | 0.75 | TAS1R3 (0.78) | LMNATAS1R3TAS1R1 | |
| SCHEMBL25517392 | 0.75 | TAS1R3 (0.78) | LMNATAS1R3TAS1R1 | |
| SCHEMBL20853657 | 0.75 | TAS1R3 (0.78) | LMNATAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236952-B2 | Preparations containing amino acids and orotic acid | Northern Innovations Holding Corp. (CA) | 2012-08-07 | — | — | US | disclosed |
| US-8236952-B2 | Preparations containing amino acids and orotic acid | Northern Innovations Holding Corp. (CA) | 2012-08-07 | — | — | US | disclosed |
| US-8236952-B2 | Preparations containing amino acids and orotic acid | Northern Innovations Holding Corp. (CA) | 2012-08-07 | — | — | US | disclosed |
| EP-2231622-A1 | PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID | Northern Innovations and Formulations Corp. (CA) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009076743-A1 | PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID | IOVATE T. & P. INC. (CA) | 2009-06-25 | — | — | WO | disclosed |
| WO-2009076743-A1 | PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID | IOVATE T. & P. INC. (CA) | 2009-06-25 | — | — | WO | disclosed |
| US-20090156812-A1 | PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID | IOVATE T. & P. INC. (CA) | 2009-06-18 | — | — | US | disclosed |
| US-20090156812-A1 | PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID | IOVATE T. & P. INC. (CA) | 2009-06-18 | — | — | US | disclosed |
| US-20090156812-A1 | PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID | IOVATE T. & P. INC. (CA) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156812-A1 | PREPARATIONS CONTAINING AMINO ACIDS AND OROTIC ACID | DDC, ODC1, OTC | GRN 3002/4885SORT1 1948/4885ALDH1A1 2765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.