Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77787 | 0.96 | TSHR (0.33) | TSHR | |
| SCHEMBL3974598 | 0.92 | TSHR (0.31) | TSHR | |
| SCHEMBL216049 | 0.77 | — | — | |
| SCHEMBL8735877 | 0.68 | ANPEP (0.39) | TSHR | |
| SCHEMBL26392989 | 0.67 | TSHR (0.31) | TSHR | |
| SCHEMBL25924946 | 0.67 | — | — | |
| SCHEMBL7143922 | 0.66 | ANPEP (0.38) | TSHR | |
| SCHEMBL214700 | 0.64 | — | — | |
| SCHEMBL5462923 | 0.64 | — | — | |
| SCHEMBL7636247 | 0.64 | TSHR (0.38) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115490743-A | Method for preparing beta-salon with high stereoselectivity | 长沙启晟合研医药科技有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-110903172-A | Method for stereoselectively synthesizing (E) -tri-substituted olefin | 温州大学 | 2020-03-24 | — | — | CN | claimed |
| CN-110878001-A | Process for the isomerization of (Z) -olefins to (E) -olefins | 温州大学 | 2020-03-13 | — | — | CN | claimed |
| US-12304889-B2 | Method for producing cis-(-)-flocino piperidol | Sumitomo Pharma Co., Ltd. (JP) | 2025-05-20 | — | — | US | disclosed |
| CN-114933624-B | Artificial synthesis method of natural product (+) -digitonin | 大连理工大学 | 2024-02-20 | — | — | CN | disclosed |
| CN-115490743-A | Method for preparing beta-salon with high stereoselectivity | 长沙启晟合研医药科技有限公司 | 2022-12-20 | — | — | CN | disclosed |
| US-20220220072-A1 | METHOD FOR PRODUCING CIS-(-) FLOCINOPIPERIDOL | Sumitomo Pharma Co., Ltd. (JP) | 2022-07-14 | — | — | US | disclosed |
| CN-110903172-B | Method for stereoselectively synthesizing (E) -tri-substituted olefin | 温州大学 | 2021-08-24 | — | — | CN | disclosed |
| WO-2020213714-A1 | METHOD FOR PRODUCING CIS-(-)-FLUOCINO PIPERIDOL | 大日本住友製薬株式会社 | 2020-10-22 | — | — | WO | disclosed |
| CN-110903172-A | Method for stereoselectively synthesizing (E) -tri-substituted olefin | 温州大学 | 2020-03-24 | — | — | CN | disclosed |
| CN-110878001-A | Process for the isomerization of (Z) -olefins to (E) -olefins | 温州大学 | 2020-03-13 | — | — | CN | disclosed |
| US-7572303-B2 | A symmetrical dialkyl carbonate, a metal, borong, silicon, or group 7 compound, a hydrogen or hydrocarbon-based fuel, an oxidizer, and a metallic cocatalyst; minimized hydrolysis; improved combustion and storage stability | OCTANE INTERNATIONAL, LTD. (US) | 2009-08-11 | — | — | US | disclosed |
| EP-0954558-B1 | FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY | ORR WILLIAM C (US) | 2006-06-14 | — | — | EP | disclosed |
| US-20050044778-A1 | Fuel compositions employing catalyst combustion structure | OCTANE INTERNATIONAL, LTD. | 2005-03-03 | — | — | US | disclosed |
| US-20040237384-A1 | Fuel compositions exhibiting improved fuel stability | OCTANE INTERNATIONAL, LTD. | 2004-12-02 | — | — | US | disclosed |
| US-6652608-B1 | Fuel compositions exhibiting improved fuel stability | OCTANE INTERNATIONAL, LTD. | 2003-11-25 | — | — | US | disclosed |
| EP-1051461-A2 | FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE | ORR, William C. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999066009-A2 | FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE | ORR WILLIAM C (US) | 1999-12-23 | — | — | WO | disclosed |
| EP-0954558-A1 | FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY | ORR, William C. (US) | 1999-11-10 | — | — | EP | disclosed |
| WO-1998026028-A1 | FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY | ORR WILLIAM C (US) | 1998-06-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220220072-A1 | METHOD FOR PRODUCING CIS-(-) FLOCINOPIPERIDOL | DHFR, DHPS, TKT | TSHR 90/4885 |
| US-12304889-B2 | Method for producing cis-(-)-flocino piperidol | FLOT1, DHFR, TKT | TSHR 123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.