Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77787 | 0.96 | TSHR (0.33) | TSHR | |
| SCHEMBL3889039 | 0.92 | TSHR (0.31) | TSHR | |
| SCHEMBL216049 | 0.77 | — | — | |
| SCHEMBL7143922 | 0.73 | ANPEP (0.38) | TSHR | |
| SCHEMBL8735877 | 0.68 | ANPEP (0.39) | TSHR | |
| SCHEMBL26392989 | 0.67 | TSHR (0.31) | TSHR | |
| SCHEMBL25924946 | 0.67 | — | — | |
| SCHEMBL7146304 | 0.65 | — | — | |
| SCHEMBL214700 | 0.64 | — | — | |
| SCHEMBL7636247 | 0.64 | TSHR (0.38) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119977814-A | Compound AX-Bn with metabolic activity improving function and preparation method thereof | 生命奇观(苏州)生物科技有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119798129-A | Synthesis method of pivalic acid 1, 3-tetramethylbutyl peroxide | 兰州助剂厂股份有限公司 | 2025-04-11 | — | — | CN | claimed |
| CN-119390968-A | Polymerization method for regulating and controlling polyketone molecular weight | 大连理工大学 | 2025-02-07 | — | — | CN | claimed |
| CN-118108978-A | Flame retardant polymer material and preparation method thereof | 广西华谊氯碱化工有限公司 | 2024-05-31 | — | — | CN | claimed |
| US-20240059678-A1 | Synthesis Method for Aminopyrimidine FAK Inhibitor Compound | HINOVA PHARMACEUTICALS INC. (CN) | 2024-02-22 | — | — | US | claimed |
| EP-4279488-A1 | SYNTHESIS METHOD FOR AMINOPYRIMIDINE FAK INHIBITOR COMPOUND | Hinova Pharmaceuticals Inc. (CN) | 2023-11-22 | — | — | EP | claimed |
| WO-2022152315-A1 | SYNTHESIS METHOD FOR AMINOPYRIMIDINE FAK INHIBITOR COMPOUND | 海创药业股份有限公司 | 2022-07-21 | — | — | WO | claimed |
| US-20040249187-A1 | Method for producing chiral amino acid derivatives | BAYER CHEMICALS AG (DE) | 2004-12-09 | — | — | US | claimed |
| US-12304889-B2 | Method for producing cis-(-)-flocino piperidol | Sumitomo Pharma Co., Ltd. (JP) | 2025-05-20 | — | — | US | disclosed |
| CN-119977814-A | Compound AX-Bn with metabolic activity improving function and preparation method thereof | 生命奇观(苏州)生物科技有限公司 | 2025-05-13 | — | — | CN | disclosed |
| CN-119948027-A | SOS1 protein degradation agent and application thereof | 领泰生物医药(绍兴)有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-115232108-B | SOS1 degradation agent and preparation method and application thereof | 领泰生物医药(绍兴)有限公司 | 2025-04-18 | — | — | CN | disclosed |
| CN-119798129-A | Synthesis method of pivalic acid 1, 3-tetramethylbutyl peroxide | 兰州助剂厂股份有限公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-119638696-A | Methods and compositions for modulating splicing | 斯基霍克疗法公司 | 2025-03-18 | — | — | CN | disclosed |
| EP-0115954-A2 | Bicyclooctane derivatives and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-08-15 | — | — | EP | disclosed |
| EP-0038131-B1 | BICYCLOOCTANE COMPOUNDS, THEIR PRODUCTION, COMPOSITIONS CONTAINING THEM AND THEIR PHARMACEUTICAL USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-08-08 | — | — | EP | disclosed |
| EP-0060523-B1 | PROCESS FOR REMOVING HYDROPEROXIDES AND ALDEHYDES FROM ALLYL-ALKYL ETHER | UNION CARBIDE CORPORATION (US) | 1984-07-18 | — | — | EP | disclosed |
| EP-0092963-A1 | Bicyclooctane derivatives and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-11-02 | — | — | EP | disclosed |
| US-4400393-A | Novel bicyclooctane compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-08-23 | — | — | US | disclosed |
| EP-0084408-A1 | Bicyclooctane compounds and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-07-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240059678-A1 | Synthesis Method for Aminopyrimidine FAK Inhibitor Compound | PTK2, PARP16, CDK6 | TSHR 2809/4885 |
| US-12304889-B2 | Method for producing cis-(-)-flocino piperidol | FLOT1, DHFR, TKT | TSHR 123/4885 |
| US-20040249187-A1 | Method for producing chiral amino acid derivatives | ADH5, AADAT, NOS2 | TSHR 3545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.