SCHEMBL3889075

SCHEMBL3889075

CO[Si](N)(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 2/20 0.38
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
POLB P06746 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
ALDH1A1 P00352 5/20 0.32
CYP1A2 P05177 2/20 0.32
ADRA2B P18089 1/20 0.32
PTGS1 P23219 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
LTA4H P09960 1/20 0.32
CYP2C19 P33261 1/20 0.32
TSHR P16473 4/20 0.31
MAPT P10636 2/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3886644 0.79 CA4 (0.38) CA4ESR1ESR2POLBCA12
SCHEMBL646249 0.75 CA4 (0.43) CA4ESR1ESR2POLBCA12
Methylamine SCHEMBL28410618 0.74 POLB (0.38) CA4ESR1ESR2POLBCA12
SCHEMBL3882939 0.74 TSHR (0.30) ESR1ESR2TSHR
SCHEMBL3894498 0.73 ALDH1A1 (0.34) ESR1ESR2ALDH1A1LTA4HTSHR
SCHEMBL648335 0.72 CA4 (0.41) CA4ESR1ESR2POLBCA12
SCHEMBL49008 0.72 CA4 (0.41) CA4ESR1ESR2POLBCA12
SCHEMBL49088 0.72 CA4 (0.41) CA4ESR1ESR2POLBCA12
SCHEMBL37986 0.72 CA4 (0.41) CA4ESR1ESR2POLBCA12
SCHEMBL27596877 0.72 CA4 (0.41) CA4ESR1ESR2POLBCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7572303-B2 A symmetrical dialkyl carbonate, a metal, borong, silicon, or group 7 compound, a hydrogen or hydrocarbon-based fuel, an oxidizer, and a metallic cocatalyst; minimized hydrolysis; improved combustion and storage stability OCTANE INTERNATIONAL, LTD. (US) 2009-08-11 US disclosed
US-20040237384-A1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2004-12-02 US disclosed